Recent Progress of Thioester Method  

作　　者：Saburo Aimoto Kenta Teruya Koki Hasegawa Takeshi Sato Kenichi Akaji Toru Kawakami 

机构地区：[1]Institute for Protein Research, Osaka University, Suita, Osaka 565-0871, Japan

出　　处：《Chemical Research in Chinese Universities》2006年第2期253-257,共5页高等学校化学研究（英文版）

基　　金：SupportedpartiallybyaGrandinAidforScientificResearchfromtheMinistryofEducation,Science,SportsandCultureofJapan(Nos.10179103and12780440).

摘　　要：Introduction The availability of site-specifically modified peptides is of vital importance for biochemical and biophysical studies. Biological methods, such as expression using bacteria, are useful. They are, however, not always applicable to the synthesis of peptides with sitespecific modifications. Chemical methods can be viable alternatives to those biological approaches. Peptides obtained by chemical and biological means,Introduction The availability of site-specifically modified peptides is of vital importance for biochemical and biophysical studies. Biological methods, such as expression using bacteria, are useful. They are, however, not always applicable to the synthesis of peptides with sitespecific modifications. Chemical methods can be viable alternatives to those biological approaches. Peptides obtained by chemical and biological means,

关 键 词：Thioester method Thiol linker PEPTIDE 

分 类 号：Q503[生物学—生物化学]