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作 者:胡盛寿[1] 王小啟[1] 许建屏[1] 孙立忠[1] 刘迎龙[1]
机构地区:[1]中国医学科学院中国协和医科大学阜外心血管病医院外科,北京100037
出 处:《中华医学杂志》2006年第11期766-770,共5页National Medical Journal of China
摘 要:目的总结心脏肿瘤的外科治疗经验。方法回顾分析中国医学科学院阜外心血管病医院近30年494例心脏肿瘤的资料,年龄43岁±16岁(4个月~78岁),其中黏液瘤432例,非黏液性良性肿瘤27例,恶性肿瘤35例。结果黏液瘤手术死亡11例(病死率2.5%),非黏液性良性肿瘤无死亡,恶性肿瘤手术死亡3例(病死率8.6%)。对1990年1月到2004年7月黏液瘤手术患者241例进行随访,失访17例,随访率为92.9%,平均随访70个月±36个月;远期死亡10例,5例死于复发,5例原因不明。恶性肿瘤完整切除10例(28.6%),大部分切除15例(42.9%),因广泛浸润转移仅做活检者10例(28.6%);平均随访时间为21个月±12个月(4~38个月);死亡18例(51.4%),均在3个月至2年内死于复发或转移;5例失访。结论外科治疗心脏良性肿瘤具有很好的近期和远期效果,恶性肿瘤外科治疗效果极差。Objective To summarize the experiences in surgical treatment of cardiac tumors. Methods The results of surgical treatment of 494 patients with cardiac tumors hospitalized from 1975 to 2004, aged 43 ± 16 (4 months to 78 years), 432 with myxoma, 27 with benign nonmyxoma, and 35 with malignant tumors, were analyzed. Results Complete resection of malignant tumor was achieved in 10 cases (28.6%), and subtotal resection was achieved in 15 cases (42.9%). or partial resection was performed based on the intra-operative condition. Only biopsy was performed in 10 patients (28.6%) because of extensive metastasis of tumor. Hospital death occurred in 11 myxoma patients (2.5%), and 3 malignant tumor patients ( 8.6% ), and none of the benign non-myxoma tumor patients. The patients were followed up for 70 ± 36 months with a follow-up rate of 92.9%. Late follow-up was performed for the 241 patients with myxoma who had underwent resection after 1990. Seventeen patients were lost to follow-up. There were 10 late deaths, 5 resulting from recurrence and 5 from unknown causes. Follow-up for malignant tumors showed 18 (51.4%) late deaths because of recurrence or metastasis, occurring 2 months to 2 years after operation. Conclusion Excellent immediate and long-term operative results can be obtained for benign cardiac tumors. However, for the patients with malignant tumors the survival chances are dismal.
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