鞍区肿瘤术后高钠血症94例的病因探讨及处理  

Pathogenesis and Treatment of Postoperative Hypernatremia in Patients with Sellar Tumors

作　　者：漆松涛[1] 郑大海[1] 潘军[1] 方陆雄[1] 陈状[1] 

机构地区：[1]南方医科大学附属南方医院神经外科,广东广州510515

出　　处：《中国临床神经外科杂志》2006年第3期129-131,共3页Chinese Journal of Clinical Neurosurgery

摘　　要：目的分析鞍区肿瘤术后高钠血症的发病机制、诊断及治疗。方法对南方医院2002年1月至2005年5月鞍区肿瘤术后发生高钠血症的94例患者的临床资料进行回顾性分析。结果368例鞍区肿瘤术后发生高钠血症94例(25.54%),死亡4例(4.26%)。结论第三脑室腹前区的手术损伤及术后尿崩症与鞍区肿瘤术后高钠血症密切相关,去除致病因素及正确纠正高渗状态是其治疗的关键。Objective To investigate the pathogenesis, diagnosis and treatment of postoperative hypernatremia in patients with sellar tumors. Method The clinical data of 94 patients with hypernatremia after total resection of sellar tumors from January 2002 to May 2005 were analysed retrospectively. Results Postoperative hypernatremia occurred in 94 of 368 patients undergoing the surgery for the treatment of sellar tumors（25.54%）. Four patients with postoperative hypernatremia died（4.26%）. Conclusions The damage to the anteroventral third ventricle due to the operation and diabetes insipidus are closely related to postoperative hypernatremia. Getting rid of the eticlogical factors and properly correcting hypertonicity are the key to treating postoperative hypernatremia.

关 键 词：鞍区肿瘤 高钠血症 发病机制 诊断 治疗 

分 类 号：R739.41[医药卫生—肿瘤] R589.41[医药卫生—临床医学]