变速牵引提高牵引成骨效率的实验研究  

Experimental Study to Enhance the Efficiency of Distraction Osteogensis by Varying the Rate

作　　者：李刚[1] 吴煜农[1] 宋晓萌[1] 万飞[2] 

机构地区：[1]南京医科大学口腔医学院口腔颌面外科,江苏南京210029 [2]南京医科大学口腔医学院病理科,江苏南京210029

出　　处：《口腔颌面外科杂志》2006年第1期16-18,共3页Journal of Oral and Maxillofacial Surgery

基　　金：江苏省自然科学基金(BK2000023)

摘　　要：目的:观察变换速度牵引兔下颌骨15mm后新骨生成的质量,探讨提高牵引成骨效率的方法。方法:新西兰白兔5只,单侧下颌骨截开。延迟5d后,以0.75mm/次、2次/d的速率牵引6d,共9mm;再以0.5mm/次、2次/d的速率牵引6d,共6mm;固定15周,新骨分别行大体、放射学和组织学观察。结果:牵引结束后新骨逐渐成熟,到固定15周时,牵引区新骨与正常骨接近。结论:变速牵引成骨能够保证新骨的良好生成,缩短牵引时间,提高应用效率。Objective： To study the ways to enhance the efficiency of distraction osteogenesis by varying the rate. Methods： 5 New Zealand rabbits were fixed distractors when they underwent unilateral mandibular osteotomy. After a latency period of 5 days, distractors were activated at a rate of 0.75 mm per time and twice per day for 6 days to 9 ram, then at a rate of 0.5 mm per time and twice per day for 6 days to the other 6 mm, and then consolidated for 15 weeks. The regeneted bone was evaluated by general observation, radiological and histological examinations. Results： The regenerated bone gradually maturated after the distraction period. At 15 weeks of consolidation, the quality of regenerated bone in the distraction gap was similar with the original bone. Conclusion： Excellent bone regeneration could be obtained following distraction osteogenesis by varying the rate, which could reduce the distraction time and enhance the efficiency.

关 键 词：牵引成骨 变速 兔 

分 类 号：R782[医药卫生—口腔医学]