原发性胃肠道恶性淋巴瘤临床分析  

Primary gastrointestinal malignant lymphoma

作　　者：秦丽君[1] 张新军[1] 温晋锋[1] 

机构地区：[1]浙江省宁波大学医学院附属医院消化内科,宁波315020

出　　处：《临床医学》2006年第3期4-5,共2页Clinical Medicine

摘　　要：目的探讨原发性胃肠道恶性淋巴瘤(PG IML)的临床表现、内镜病理组织学特点及治疗方法。方法回顾性总结分析病理组织学证实的21例PG IML患者的临床和内镜资料。结果21例患者主要症状为腹痛、纳差、腹块、便血,胃是PG IML最常见的发生部位,内镜下的表现为肿块性、溃疡性及弥漫浸润性损害,内镜活检确诊PG IML共10例。21例均为非霍奇金淋巴瘤,其中10例为粘膜相关淋巴组织淋巴瘤。结论PG IML以腹痛为主要表现,胃的发生率最高,内镜下表现与溃疡及癌难以区分,主要病理组织学类型为MALT型结外边缘区B细胞淋巴瘤,临床进一步超声内镜检查,结合病理有助于最终确诊。预后较胃肠道其他肿瘤好。Objective To investigate the clinical manifestation, pathological feature of endoscope and healing methods in the primary gastrointestinal malignant lymphoma （PGIML）. Methods Retrospectively summarized and analyzed the clinical and endoscope data of 21 patients with PGIML confirmed by pathology. Results In the 21 patients,the major symptoms were abdominal pain,anorexia, abdominal distention and hematochezia. The common locus was stomach and endoscope manifestations were intumescent, ulcerative and diffusely infiltrative lesion,respectively. Ten patients with PGIML were diagnosed by endoscope biopsy. Twenty -one patients were all certified non Hodgkin lymphoma,including 10 cases of mucosa associated lymphoid tissue（MALT） lymphoma. Conclusion In the PGIML patients,the most common clinical symptom is abdominal pain, and the most common location is stomach. There are no significant differences among ulcer,tumor and PGIML under endoscope. Extra nodal marginal zone B - cell lymphoma of MALT is the main histopathologic feature. The further ultrasound endoscopy binding relative pathology can contribute to eventual diagnosis. The prognosis of PGIML is better than the other tumors of gastrointestine.

关 键 词：恶性淋巴瘤 胃肠道 临床分析 

分 类 号：R735[医药卫生—肿瘤] R735.2[医药卫生—临床医学]