肝动脉栓塞化疗联合射频消融术治疗原发性肝癌  

Combination of transcatheter arterial chemoembolization and CT-guided radiofrenquency ablation in treating advanced hepatocellular carcinoma

作　　者：曾沛强[1] 吴泽建[1] 黄仲初[2] 

机构地区：[1]东莞市人民医院外科,广东省东莞523018 [2]广东省广州医学院第二附属医院外科

出　　处：《中国基层医药》2006年第2期259-260,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的探讨肝动脉栓塞化疗联合CT导向下的射频消融治疗中、晚期原发性肝癌的疗效。方法40例中、晚期原发性肝癌患者分为经导管肝动脉栓塞化疗组(TACE组,20例)和肝动脉栓塞化疗联合CT导向下的射频消融治疗组(联合组,20例)。结果TACE组肿瘤完全坏死率、复发率及1年存活率分别22.5%(9/40)、37.5%(15/40)和75.0%(30/40),联合治疗组分别为90.0%(36/40)、12.5%(5/40)和90.0%(36/40)。两组间完全坏死率、初次复发率及1年生存率的差异均有显著意义(P值分别为0.002、0.003、0.008)。结论肝动脉栓塞化疗联合CT导向下的射频消融治疗原发性肝癌的疗效明显优于单纯栓塞治疗。Objective To investigate the therapeutic effect of transcatheter arterial chemoembelization （TACE） combined with CT-guided percutaneous radiofrequency ablation（PRFA） in treating advanced primary hepatoccllular carcinoma. Methods 40 cases with advanced primary hepatocellular carcinoma were randomly divided into TECA group（ n = 20） and TACE and PRFA group（ n = 20）. Results The complete necrosis rate of tumor, the recurrence rate and one-year survival rate were 22.5% （9/40）,37.5% （15/40） and 75.0% （30/40）,respectively in TACE group and 90.0% （36/40）, 12.5% （5/40） and 90.0% （36/40）,respectively in TACE and PRFA group. There were significant statistical differences between the two groups（P value were 0. 002,0. 002 and 0. 008, respectively）. Conclusion The therapeutic effects of TACE combined with CT-guided PRFA show better results than that of TACE alone.

关 键 词：肝细胞癌 射频消融术 评价研究 原发性肝癌 肝动脉栓塞化疗 

分 类 号：R735.7[医药卫生—肿瘤]