泛素/26S蛋白酶体途径与显花植物自交不亲和反应  

The Ub/26S Proteasome Pathway and Self-incompatible Responses in Flowering Plants

作　　者：于晓敏[1] 蓝兴国[1] 李玉花[1] 

机构地区：[1]东北林业大学花卉生物工程研究所,哈尔滨150040

出　　处：《植物学通报》2006年第2期197-206,共10页Chinese Bulletin of Botany

基　　金：国家自然科学基金(30371189);国家863计划(2001AA246102)

摘　　要：植物的生长和发育离不开短命调控蛋白的有选择性降解,其中一种重要的降解方式就是泛素/26S蛋白酶体途径。在这个途径中,泛素(ubiquitin)和26S蛋白酶体起着至关重要的作用,需要被降解的蛋白会通过E1-E2-E3酶接合反应由Ub进行标记,随后标记蛋白会被26S蛋白酶体识别并降解。自交不亲和反应也正是通过此途径实现的,ARC1(armrepeatcontaining1)和SCFs(skp1-cul1-F-box-proteins)作为E3s分别在孢子体自交不亲和和配子体自交不亲和反应中起作用。本文综述了就泛素/26S蛋白酶体途径的组成及其在自交不亲和反应中的作用。Plant growth and development is generally controlled by selective removal of short-lived regulatory proteins. One major pathway is represented by the ubiquitin （Ub）/26S proteasome pathway. In this pathway, ubquitin and 26S proteasome play essential roles. Ub is attached to proteins destined for degradation by a 3-step enzymatic （E1-E2-E3） conjugation cascade, and the resulting Ub- protein conjugates are then recognized and degraded by the 26S proteasome. The arm repeat-containing 1 （ARCI） and the skpl-cull-F-box （SCF） proteins, belonging to the family of E3 Ub ligases, function in both the sporophytic and gametophytic self-incompatible responses, respectively. This review highlights the recent progress toward understanding the role of the Ub/26S proteasome pathway during self-incompatible responses.

关 键 词：26S蛋白酶体 蛋白质水解 泛素 自交不亲和性 

分 类 号：Q944.44[生物学—植物学]