中国延边朝鲜族人群PentaD、E基因座的遗传多态性  

Genetic polymorphisms of Penta D and E loci in Korean racial Chinese of Yanbian area in China

作　　者：许青松[1] 张永吉[1] 崔弘 崔彦[1] 

机构地区：[1]延边大学医学部基础医学院法医学教研室,吉林省延吉133000

出　　处：《中华医学遗传学杂志》2006年第2期234-235,共2页Chinese Journal of Medical Genetics

摘　　要：目的了解中国吉林延边地区朝鲜族人群PentaD和PentaE短串联重复序列基因座的遗传多态性分布,获得相应群体遗传学数据。方法应用PCR扩增片段长度多态性分析方法对100名无血缘关系的朝鲜族个体进行调查。结果在PentaD基因座,观察到8个等位基因及22种基因型;在PentaE基因座,观察到16个等位基因及35种基因型。结论两个基因座等位基因片段多态性分布均符合Hardy-Weinberg平衡定律,而且显示很高的个人识别能力。所得数据资料可为中国朝鲜族人群的法医学个人识别、亲子鉴定及遗传学研究提供依据。Objective To analyze genetic polymorphisms of Pcnta D and E loci in Korean racial Chinese of Yanbian area. Methods One hundred unrelated individuals of Korean racial Chinese were analyzed by methods of PCR and restriction fragment length polymorphism. Results Eight alleles and 22 genotypes were observed from Penata D locus, and 16 alleles and 35 genotypes were observed from Penta E locus. Conclusion The distribution of two locus genotypes in Korean racial Chinese of Yanbian area met Hardy-Weinberg equilibrium. And the obtained data can be used to individual identity, paternity testing and the study of Korean ethnic group of Chinese population.

关 键 词：基因座 中国朝鲜族 遗传多态性 

分 类 号：R394[医药卫生—医学遗传学]