魔芋葡甘聚糖接枝共聚物的合成及其抗菌活性  

Preparation and Antimicrobial Activity of Grafted Polymer of Konjac Glucomannan with Methacryoxylethyl Benzyl Dimethyl Ammonium Chloride

作　　者：徐霞[1] 杨秦欢[1] 陆爱霞[1] 李正军[1] 何壮志[1] 林芳[1] 张廷有[1] 

机构地区：[1]四川大学皮革化学与工程教育部重点实验室

出　　处：《林产化学与工业》2006年第1期75-78,共4页Chemistry and Industry of Forest Products

基　　金：河南省教育厅自然科学研究计划资助项目(2004922008);教育部博士点基金项目(20050610047)

摘　　要：考察了一种实验室自制的魔芋葡甘聚糖季铵盐衍生物(KGM-g-DMAE-BC)的合成以及抗菌性能。正交试验优选出的最佳合成条件为:反应温度70℃,单体质量比(mKGM∶mDMAE-BC)1∶5,引发剂用量0.7 mmol/L,反应时间3 h。悬菌定量实验结果表明:KGM-g-DMAE-BC(接枝率为38.5%)对大肠杆菌、金黄色葡萄球菌及白色念珠菌有较强的杀菌作用,在振荡作用15 m in后,平均灭杀率分别为99.99%、94.26%和99.99%。The grafted polymer of konjac glucomannan （KGM） with methacryloxylethyl benzyl dimethyl ammonium chloride （KGM-g-DMAE-BC） had been prepared and its antibacterial activity was investigated. The optimum technological conditions were： reaction time 3 h, temperature 70 ℃, rnKcM： mDMAE-BC 1 ： 5 and dosage of initiator 0. 7 mmol/L. The KGM-g-DMAE-BC was confirmed by Fourier-transform infrared spectroscopy （FT-IR）. Antibacterial activities of KGM-g-DMAE-BC against a variety of microorganisms had been examined by quantitative suspension test using shaking flask. The obtained polymer was inhibitive against gram-negative bacteria （Escherichia coli ）, gram-positive bacteria （Staphylococcus aureus ） and fungus （Candida albicans）, at becteriostatic rates of 99.99 %, 94.26 %, 99.99%, respectively.

关 键 词：魔芋葡甘聚糖 季铵盐 接枝共聚 抗菌 

分 类 号：TQ91[化学工程]