乳腺癌前哨淋巴结活检的临床应用研究  

Clinical significance of sentinel lymph node biopsy in breast cancer

作　　者：熊杰[1] 胡勇军[1] 沈雄山[1] 李卫民[1] 黄正斌[1] 樊立[1] 陈纲琳[1] 

机构地区：[1]湖北省孝感市中心医院普外科,432000

出　　处：《临床外科杂志》2006年第3期152-153,共2页Journal of Clinical Surgery

摘　　要：目的探讨乳腺癌前哨淋巴结活检术(SLNB)在临床应用中的价值。方法应用亚甲蓝染色法对58例乳腺癌患者先行SLNB,随后行乳腺癌常规外科手术。结果58例患者中前哨淋巴结(SLN)检出率为93.1%,准确率为96.3%,假阴性率为5.71%,假阳性率为0;操作者的学习曲线、患者的年龄、原发肿瘤的部位影响SLN的检出率(P<0.05);肿瘤的大小、病理类型不影响SLN的检出率(P>0.05)。结论乳腺癌SLNB能够准确地预测乳腺癌患者腋窝淋巴结(ALN)的转移情况。Objective To explore the clinical value of sentinel lymph node biopsy （SLNB） in breast cancer. Methods By using methylene blue staining method, SLNB was performed on 58 patients with breast cancer, followed by routine surgical operation for breast cancer. Results The sentinel lymph nodes （SLN） were found in 54 （93.1% ） of 58 patients with the accuracy being 96.3 %. The false - negative rate was 5.71% and false - positive rate 0, The studying curve, the patients＇ age and the tumor position were related with the identification of SLN at operation （ P 〈 0.05）, but the tumor size and the pathologic classification were not associated with intraoperative detective rate of the SLN （ P 〉 0.05）. Conclusion SLNB could accurately predict the metastasis of ALN in the patients with breast cancer.

关 键 词：乳腺癌 前哨淋巴结 活组织检查 

分 类 号：R737.9[医药卫生—肿瘤]