CT引导肺穿刺组织学与印片细胞学的联合应用  

The united application of histology and cytology in transthoracic needle biopsy under CT guidance .

作　　者：贺泽文 唐铁钢 胡慧玲 

机构地区：[1]湘潭市中心医院肿瘤科,湖南湘潭411100

出　　处：《现代肿瘤医学》2006年第4期406-407,共2页Journal of Modern Oncology

摘　　要：目的评价CT引导下肺穿刺同时行组织学与印片细胞学检查的诊断价值和并发症。方法收集134例CT引导肺部穿刺活检病例作回顾性分析。统计印片细胞学、组织学以及2者结合的敏感性和并发症,并分析其影响因素。结果110例穿刺确诊为恶性肿瘤。穿刺未发现癌细胞者22例,后经手术和随访证实其中假阴性2例。组织学敏感性为82.1%(92/112),印片细胞学敏感性为87.5%(98/112),二者结合敏感性为98.2%(110/112),假阴性率为9.1%(2/22)。气胸发生率为7.5%(10/134),出血、喀血率为11.9%(13/134),仅有2例出血较多,需紧急处理。结论CT引导经皮肺穿刺是敏感性高和安全的定性诊断方法,如同时行组织学及印片细胞学检查,可提高诊断的敏感性,降低假阴性。Objective To evaluate the diagnostic value and complication of transthoracic needle biopsy of thoracic masses and nodules under CT guidance. Methods A total of 134 patients who ander went transthoracic needle biopys under CT guidance were collected. Sensitivity of histology, cytology and two unions, complication and false - negative rate were analyzed. Results Biopsies in 110 cases yielded malignant lesions, carcinoma cells were not found in 22 cases,the remaining 2 cases were found to have false - negative result as the case were proved to be cancer by operation and follow-up later. Sensitivity of histology was 82.1%, sensitivty of cytology was 87.5% ,sensitivty of two unions was 98.2% ,false - negative rate was 9.1% ,pneumothorax occure was 7.5% ,bleeding and hemoptysis rate 11.9%, only 2 patients were necessary to be treated . Conclusion CT - guided transthoracic biopsy is a safe and valuable diagnostic method with high sensitivty. If histology and cytology are examined at the same time, sensitivty rate could be raised and false - negative rate could be reduced.

关 键 词：CT引导 活组织检查 肺部疾病 组织学 细胞学 

分 类 号：R730[医药卫生—肿瘤]