β-环糊精与聚乳酸的包合物的制备与表征  

Formation and Characterization of Polylactide and β-cyclodextrin Inclusion Complex

作　　者：杨凯声[1] 谢德明[1] 孙尉翔[1] 

机构地区：[1]暨南大学生物医学工程系,广东广州510632

出　　处：《材料科学与工程学报》2006年第2期267-269,共3页Journal of Materials Science and Engineering

基　　金：国家基础研究计划"973"计划资助项目(G1999054306)

摘　　要：采用超声波与溶剂协同作用,制备了β-环糊精(-βCD)与聚乳酸(PLA)包合物,探讨了-βCD与PLA的摩尔比例、PLA分子量大小等因素对包合物形成的影响,并通过采用FTIR、DSC、TG以及X-射线粉末衍射分析证实了包合物的形成。发现PLA分子量低于100,000时,制备的-βCD/PLA包合物容易分散于水中形成胶体溶液,PLA分子量达到500,000时,形成的包合物在水中成块状析出。接触角测试结果表明,包合物亲水性明显增强。DSC分析表明,随包合物中-βCD含量增加,其Tg逐渐降低。The inclusion complex （IC） of β-cyclodextrin and polylactide was formed by a solutlon-ultrasonic technique. The effects of proportion between β-CD and PLA, and the molecular weight of PLA on the formation of the inclusion complex were evaluated. Formation of the inclusion complex was verified by Fourier transform infrared （FTIR） spectroscopy, differential scanning calorimetry （DSC）, and wideangle X-ray diffraction （WAXD）. The inclusion complex whose molecular weight is lower than 100,000 dispersed in water, whereas the inclusion complex whose molecular weight reaches 500,000 agglomerated in water. Results of surface contact angle showed that the hydrophilicity of the inclusion complex was obviously improved. Thermogravimetric analysis indicated that the inclusion complex had a lower glass transition temperature when compared to polylactide.

关 键 词：Β-环糊精 聚乳酸 溶液法 包合物 

分 类 号：TQ31[化学工程—高聚物工业]