癫癎患儿血清催乳素变化的研究  

The study on change of serum prolactin in epileptic Children

作　　者：李姝红[1] 荣道建[2] 于一兵[2] 吴秀清[1] 高云霞[2] 赵昕[1] 

机构地区：[1]沈阳市儿童医院,辽宁沈阳110034 [2]中国医科大学附属第二医院,辽宁沈阳110004

出　　处：《中国小儿急救医学》2006年第2期116-118,共3页Chinese Pediatric Emergency Medicine

摘　　要：目的探讨癫发作和抗癫药物治疗对催乳素(PRL)分泌的影响。方法采用放射免疫法(RIA)检测49例患儿癫发作期间及抗癫药物治疗后血清PRL水平。结果癫发作后血清PRL水平要较正常对照组明显升高;癫发作类型和血清PRL水平升高之间具有明显的相关性;各种抗癫药物对血清PRL水平的影响不同。结论癫发作和抗癫药物治疗均明显影响垂体PRL的分泌功能。Objective To discuss the effect of seizures and anticonvulsants on proactin （PRL） secretion. Methods The level of serum PRL was measured by radioimmunoassay in 49 patients after epileptic seizures and anticonvulsant treatment. Results The level of serum PRL in epileptic patients was markedly higher than that of the controls. The rise of serum PRL levels was correlated significantly with the types of epileptic seizures. The level of serum PRL was changed by the different anticonvulsant drugs. Conclusion Epileptic seizures and anticonvulsant treatment may affect the secrel;ion of PRL in the pituitary.

关 键 词：癫痫 抗癫痫药 催乳素 放射免疫法 

分 类 号：R742.1[医药卫生—神经病学与精神病学]