186例青年人肺癌化疗与放疗疗效及影响预后因素分析  

Cgemotherapy and Rpadiotherapy in YoungPatients with Lung Cancer

作　　者：张孟秋 张秀丽 于开君[1] 赵丽萍 

机构地区：[1]白求恩医科大学第三临床学院

出　　处：《中国肿瘤临床》1996年第7期509-511,共3页Chinese Journal of Clinical Oncology

摘　　要：年龄在３５岁以下失去手术机会的青年人肺癌１８６例，单纯化疗８４例，先化疗后放疗６１例，先放疗后化疗３８例，单纯放疗３例。化疗综合放疗可明显提高缓解率（Ｐ＜０．０１），总有效率为７３．１２％。中位生存期为１３个月，≥１、≥２、≥５年生存率分别为４６．２％、２４．７％、８．１％。对影响预后的因素进行了分析。结果表明：血清中ＣＥＡ、误诊及机体免疫机能对其预后有一定影响。One hundred and eithty-six young patients under 35 years of agewith unresectable lung cancer were analyzed.Chemotherapy was administrated solely in 84 cases,chemotherapy followed by radiotherapy in 61,chemotheraopy afterradiotherapy in 38and radiotherapy alone in 3.Of these, those treated withchemotherapy combined with radiotherapy achieved the best result(P<0.01).The≥1-,≥2-,≥5-year survival rates were 46. 2%,24. 7% and 8. 1% respectively,witha mean survival duration of 13 months. It was found that serum CEA level,misdiagnosis and immunity are the main factors influencing prognosis.

关 键 词：肺肿瘤 药物疗法 放射疗法 预后 青年 

分 类 号：R734.205[医药卫生—肿瘤]