复方甲硝唑口腔复合膜的制备及质量控制  

Preparation and Quality Control of Oral Cavity Film of Motronidazole Compound

作　　者：李晓红[1] 董慧贤[1] 倪雁[1] 陈贵文[1] 孙莉 

机构地区：[1]哈尔滨医科大学附属第一医院药学部,黑龙江省牡丹江林业中心医院

出　　处：《中国药房》1996年第1期18-19,共2页China Pharmacy

摘　　要：复方甲硝唑口腔复合膜以ＰＶＡ＿（１７～８８）－ＣＭＣＮａ（２：１）为药膜材料、ＰＶＡ＿（１７～８８）为覆盖膜材料，采用涂膜法制备，用紫外分光光度法测定含量平均回收率１０２．９％，Ｒ８０＝１．１６％。Smear method was used to prepare oral cavity film of metronidazole compound with PVA17～88-CMCNa(2:1) as the material of drug film, PVA17～88 as the coating material. UV-spectrophotometry was used to determine the content of metronidazole. The average recovery was 102.9%,RSD=1.16%.

关 键 词：药物 复合膜 制备 质量控制 甲硝唑 

分 类 号：TQ460.4[化学工程—制药化工]