热疗联合介入治疗晚期肝癌临床观察  

Clinical Observation on Hyperthermia Combined with Interventional Therapy for Advanced Liver Cancer

作　　者：孙雪飞[1] 

机构地区：[1]吉林大学中日联谊医院,吉林长春130021

出　　处：《肿瘤学杂志》2006年第2期145-147,共3页Journal of Chinese Oncology

摘　　要：[目的]比较热疗联合介入栓塞化疗与单纯介入栓塞化疗治疗晚期肝癌的近期疗效和毒副反应。[方法]将44例晚期原发性肝癌患者随机分为两组,每组22例,A组采用热疗联合介入栓塞化疗;B组采用单纯介入栓塞化疗。[结果]A组有效率81.82%,中位生存期11.6个月,1年生存率为45.5%;B组有效率63.64%,中位生存期8.3个月,1年生存率为27.3%(P<0.05);两组毒副反应没有显著性差异。[结论]介入联合热疗治疗晚期肝癌疗效优于单纯介入治疗,且不增加副作用,是治疗晚期肝癌的一种有效途径。[Purpose]To compare the short-term effect and toxicity of hyperthermia combined with interventional therapy and interventional therapy alone for advanced liver cancer. [Method] Forty-four patients were randomly divided into 2 groups, each group with 22 cases. Group A was treated with hyperthermia combining with interventional therapy; Group B, with interventional therapy alone. [Result] The response rate in group A was 81.82%, median survival, 11.6 months; 1-year survival rate,45.5%. The response rate in group B was 63.64%; median survival, 8.3 months; 1-year survival rate, 27.3%（P〈0.05）. There was no significant difference in toxicity between group A and B.[Conclusion] Interventional therapy combined with hyperthermia has superior effect than interventional therapy alone, without increasing toxicity. It is an effective therapy for advanced liver cancer.

关 键 词：癌 肝细胞 肝肿瘤 高温 诱发 栓塞 治疗性 放射学 介入性 

分 类 号：R735.7[医药卫生—肿瘤]