The impact of synapsins on synaptic plasticity and cognitive behaviors  

作　　者：Lin ZHANG Zhong-Xin ZHAO 

机构地区：[1]Department of Neurology , Changzheng Hospital , Shanghai 200003, China

出　　处：《Neuroscience Bulletin》2006年第1期63-67,共5页神经科学通报（英文版）

摘　　要：Synapsins are a family of phosphoproteins specifically associated with the cytoplasmic surface of the synaptic vesicle membrane, appearing to regulate neurotransmitter release, the formation and maintenance of synaptic contacts. They could induce the change of the synaptic plasticity to regulate various adaptation reactions, and change the cognitive behaviors. So we presume that if some cognitive behavior are damaged, synapsins would be changed as well. This gives us a new recognition of better diagnosis and therapy of cognitive disorder desease.Synapsins are a family of phosphoproteins specifically associated with the cytoplasmic surface of the synaptic vesicle membrane, appearing to regulate neurotransmitter release, the formation and maintenance of synaptic contacts.They could induce the change of the synaptic plasticity to regulate various adaptation reactions, and change the cognitive behaviors. So we presume that if some cognitive behavior are damaged, synapsins would be changed as well. This gives us a new recognition of better diagnosis and therapy of cognitive disorder desease.

关 键 词：SYNAPSIN synaptic plasiticity cognitive behavior cognitive disorder 

分 类 号：Q427[生物学—神经生物学]