鼻咽癌放疗完全缓解后腔内照射补量  

Intracavitary Brachytherapy Boost for Complete Responders to Traditional Curative Radiotherapy

作　　者：赵水喜[1] 王迎选[2] 崔书祥[2] 曹京旭[1] 郑静晨[1] 

机构地区：[1]武警总医院肿瘤科,北京100039 [2]解放军总医院放疗科

出　　处：《肿瘤防治研究》2006年第4期275-276,共2页Cancer Research on Prevention and Treatment

摘　　要：目的 研究鼻咽癌放疗完全缓解后腔内照射补量的剂量效应关系。方法 1992年2月～1999年12月92例根治性放疗65～70Gy后完全缓解T1、T2患者行近距离腔内补量照射，1975年11月～2000年12月收治的根治性放疗后完全缓解未进一步治疗的T1、T2患者206例为对照。结果 T1、T2根治性放疗后完全缓解未加量组、根治性放疗后完全缓解腔内补量组5年生存率分别为78．28％、85．14％。根治性放疗后完全缓解腔内补量〈80Gy者与≥80Gy者5年生存率分别为78．2％、85．9％。结论 早期鼻咽癌传统根治性放疗后相对抗拒肿瘤腔内补量提高了局部控制，可进一步改善生存。Objective To evaluate the result of intracavitary brachytherapy boost for nasopharyngeal carcinoma. Methods For patients with carcinoma of nasopharynx in T1 ,T2 stage, from February 1992 to December 2000, 92 patients delivered intracavitary brachytherapy boost for complete responders to traditionale curative radiotherapy; To compare the efficacy of intracavitary brachytherapy boost for complete responders, from November 1975 to December 2000, 206 patients with complete responder to curative radiotherapy were observed. Results For complete responder and boost for complete responder, overall survival at 5 years is 78. 28% ,85. 14%. boost for complete responder, total dose 〈80Gy and ≥80Gy, overall survival at 5 years is 78. 2%,85. 9%. Conclusion Intracavitary brachytherapy boost for relative resistant to traditionale curative radiotherapy have improved tumor control.

关 键 词：鼻咽肿瘤 腔内照射 补量 

分 类 号：R739.63[医药卫生—肿瘤]