胰腺癌^(18)F-脱氧葡萄糖PET/CT的影像表现及其诊断价值  

^(18)F-FDG PET/CT findings in pancreatic carcinoma and their diagnosis value

作　　者：王中秋[1] 卢光明[1] 朱虹[2] 常林风[2] 吴江[2] 郑玲[1] 王俊鹏[1] 秦莉萍[2] 

机构地区：[1]南京军区南京总医院医学影像科,210002 [2]南京军区南京总医院核医学科,210002

出　　处：《医学研究生学报》2006年第4期359-361,364,共4页Journal of Medical Postgraduates

摘　　要：目的:探讨胰腺癌18F脱氧葡萄糖(FDG)PET/CT显像的影像表现及PET/CT对胰腺癌的诊断价值。方法:26例胰腺恶性病变和6例胰腺炎患者均经病理和临床等综合手段证实,并均行18FFDG全身PET/CT显像,观察胰腺癌的PET/CT表现,结合手术病理和临床结果,分析PET/CT对胰腺癌诊断的敏感性、特异性和准确性。结果:胰腺恶性病变26例,其中20例为胰腺癌,3例为胰腺癌手术后复发,2例为胰腺转移癌,1例为交界性肿瘤(潜在恶性);胰周和腹膜后淋巴结转移8例,腹膜腔及肠系膜转移4例,肝脏转移7例,脊椎等其他骨转移2例,其他部位转移2例。胰腺恶性病变的PET/CT表现为Ⅰ型21例,Ⅱ型3例,Ⅲ型2例,Ⅳ型0例。PET/CT对胰腺疾患诊断的敏感性为96.2%,特异性为66.7%,准确性为87.5%。结论:胰腺癌18FFDGPET/CT的影像表现可多种形式,其中Ⅰ型占80.8%,为典型表现;PET/CT对胰腺癌的诊断价值高,但仍存在少部分假阳性和假阴性。Objective：To describe the findings and to assess the diagnosis value of positron emission tomography/computed tomography （PET/CT） with fluorine-18-labeled fluorodeoxyglucose （FDG） for pancreatic carcinoma. Methods： FDG PET/CT was performed in twenty six patients having pancreatic malignent neoplasm and six patients having pancreatitis, all proved by comprehensive methods as surgery and clinical diagnosis. Images were interpreted and compared with the histopathologic findings at surgery or with clinical follow-up findings. The sensitivity, specificity and accuracy of PET/CT diagnosis were analyzed. Results： Twenty six patients had pancreatic malignant neoplasm, among whom 20 were pancreatic carcinomas, 3 were postoperation recurrence of pancreatic carcinoma, 2 were metastatic carcinoma of pancreas and 1 was potential malignancy. Eight cases were neal lymph node, 4 in peritoneal cavity and mesentery, 7 in metastatic in parapancreas and retroperitohepatic metastatic, and 2 in bone. The PET/CT findings of 26 patients with pancreatic malignant neoplasm showed that there were 21 in Type Ⅰ , 3 in Type Ⅱ , 2 in Type Ⅲ and 0 in Type Ⅳ, respectively. The sensitivity, specificity and accuracy of PET/CT diagnosis were respectively 96.2% ,66.7% and 87.5%. Conclusion： Imaging demonstration of PET/CT for pancreatic carcinoma varies in modality, and Type Ⅰ （80.8%） was typical. PET/CT was of great value for the diagnosis of pancreatic carcinoma, although there were still a few false positive and false negative findings.

关 键 词：胰腺癌 阳电子发射体层摄影术 计算机X线断层照像术 脱氧葡萄糖 

分 类 号：R735.9[医药卫生—肿瘤]