1,2-缩水-3,4-二-O-苄基-6-脱氧-β-L-塔罗吡喃糖的合成  

SYNTHESIS OF l,2-ANHYDRO-3,4-DI-O-BENZYL-6-DEOXY-0-L -TALOPYRANOSE

作　　者：甘中红 孔繁祚[1] 徐国铮[2] 王玉珍[2] 

机构地区：[1]中国科学院生态环境研究中心,北京100085 [2]中国科学院化学研究所,北京100080

出　　处：《环境化学》1996年第2期174-178,共5页Environmental Chemistry

基　　金：攀登计划项目

摘　　要：以L-鼠李糖为原料.首先合成(?)脱氧塔罗糖的衍生物(5),再经过一系列反应得到2-O-乙酸基-3,4-(?)-O-(?)基-6-脱氧-α-L-塔罗吡喃糖氯代物(9),在叔丁醇钾的作用下,化合物9很容易关环得到最终产物1,2-内醚糖.The title compound was synthesized from L-rhamnose by a series of steps. The key intermediate for the synthesis was 2-O acetyl-3, 4-di-O-benzyl 6-deoxy-a-L-talopyra nosyl chloride, which was converted into the target compound by ring closure with potassium tert-butoxide. The 1H NMR spectrum of the anhydro sugar was determined by the use of single frequency decoupling. The new compounds obtained in the synthesis were identified by their 1H NMR spectra,elemental analysis,mass spectra and optical rotation.

关 键 词：塔罗糖 内醚糖 脱氧塔罗糖 塔罗吡喃糖 合成 

分 类 号：TQ28[化学工程—有机化工] Q532.3[生物学—生物化学]