三腔二囊管联合脑垂体后叶素治疗肝硬化并上消化道大出血  

Sengstaken-Blackmore Tube Pmus Posterior Pituitary in the Treatment of Hemorrhage Due to Cirrhosis with Esophageal and Fundal Varices

作　　者：高作文[1] 

机构地区：[1]解放军第86医院感染科,安徽当涂243100

出　　处：《实用临床医学（江西）》2006年第4期29-30,共2页Practical Clinical Medicine

摘　　要：目的:探讨三腔二囊管联合脑垂体后叶素治疗肝硬化食道胃底静脉曲张破裂大出血的临床疗效。方法:78例肝硬化食道胃底静脉曲张破裂大出血患者随机分为两组:治疗组和对照组,每组各39例。两组患者均予禁食、补充有效血容量、维持水电解质酸碱平衡等。在此基础上,治疗组加用三腔二囊管联合脑垂体后叶素治疗,对照组加用生长抑素治疗。观察两组48 h的止血率及控制出血的时间。结果:治疗组有效率为84.6%,对照组有效率为89.7%,两组比较,无显著性差异(P>0.05),治疗组控制出血的时间短于对照组(P<0.05)。结论:三腔二囊管联合脑垂体后叶素治疗肝硬化消化道大出血是一种廉价而有效的方法。Objective： To compare Sengstaken-Blackmore tube plus posterior pituitary to somatostatin for the treatment of large hemorrhage due to cirrhosis with esophageal and fundal varices. Methods：Patients were randomized for treatment with the combination of Sengstaken-Blackmore tube with posterior pituitary（n= 39）, or somastatin（n= 39）, the clinical response were assessed at 48 hours after treatments. Results： There were no significant difference of effective rate between the two groups （84.6% ：89.7%） （P〉0.05）. The combination therapy controled hemorrhage earlier than somatostatin did. Conclusion： The combination therapy is effective in controlling hemorrhage caused by cirrhosis with esophageal and fundal varices.

关 键 词：三腔二囊管 脑垂体后叶素 肝硬化 静脉曲张 大出血 

分 类 号：R575.2[医药卫生—消化系统]