一侧大脑前动脉发育不良的经颅多普勒超声检测与分析  

Unilateral hypogenesis of anterior cerebral artery: transcranial Doppler ultrasonography and analysis

作　　者：阮利江[1] 黄伟[1] 王岩[1] 余志敏[1] 孙淑娟[2] 

机构地区：[1]深圳市宝安区西乡人民医院超声科,518102 [2]深圳市宝安区西乡人民医院神经内科,518102

出　　处：《中国脑血管病杂志》2006年第4期153-156,共4页Chinese Journal of Cerebrovascular Diseases

摘　　要：目的应用经颅多普勒超声(TCD)分析一侧大脑前动脉发育不良(细小支)的血流动力学特点并探讨TCD的诊断价值。方法对经TCD和磁共振血管造影(MRA)筛查的28例一侧大脑前动脉发育不良的患者,进行颈动脉压迫试验前后细小侧和对侧大脑前动脉交通前段(ACA-A1)的血流动力学改变的观察,并与28例健康者(对照组)比较。结果28例患者细小侧ACA-A1血流速度(62±17)cm/s显著低于对照组(87±15)cm/s(P<0.01),对侧ACA-A1血流速度(123±13)cm/s显著高于对照组(P<0.01),细小侧ACA-A1血流速度平均为对侧的1/2。压迫对侧颈总动脉后,细小侧ACA-A1血流速度增高倍数(3.08±0.51)显著高于对照组(1.97±0.25)(P<0.01),对侧ACA-A1血流速度增高倍数(1.35±0.11)显著低于对照组(P<0.01),细小侧ACA-A1血流速度增高幅度平均为对侧的2倍以上。结论根据颈总动脉压迫试验前后双侧大脑前动脉的血流动力学改变,结合血流信号强度、血流分布等辅助指标,TCD可诊断一侧大脑前动脉发育不良。Objectives To analyze the hemodynamic characteristics in patients with unilateral hypogenesis of anterior cerebral artery （ACA） using transcranial Doppler ultrasonography （TCD） and to discuss the diagnostic value of it. Methods Twenty-eight patients with unilateral hypogenesis of ACA were confirmed by TCD and magnetic resonance angiography （MRA）. The characteristics of hemodynamic changes were observed in hypogenetic side and contralateral anterior cerebral artery A1 segment （ ACA-A1 ） before and after compression of the common carotid artery. They were also compared with 28 normal controls. Results The blood flow velocity of the hypogenetic side ACA-A1 （62 ± 17） cm/s of the 28 patients was significantly lower than that of the control group [ （87 ± 15） cm/s; P〈0. 01 ] ; the blood flow velocity of the contralateral ACA-A1 （123 ± 13 ） cm/s was significantly higher than that of the control group （P 〈 0. 01 ）. The average blood flow velocity of the hypogenetic side ACA-A1 was almost half of the contralateral ACA-AI. After compressing the common carotid arteries respectively, the blood flow velocity of the hypogenetic side ACA-A1 increased for several times （3.08 ±0. 51 ）, and it was significantly higher than that of the control group （ 1.97 ±0. 25 ; P 〈0. 01 ） ; the blood flow velocity of the contralateral side ACA-A1 increased for several times （ 1.35 ± 0. 11 ）, and it was significantly lower than that of the control group （P 〈 0. 01 ） ; the average blood flow velocity of the hypogenetic side ACA-A1 was more than 2 times of the contralateral ACA-A1. Conclusion According to hemodynamic changes before and after compression of the common carotid artery, together with the signal strength of blood flow, and the distribution of blood flow, TCD may defect unilateral hypogenesis of ACA.

关 键 词：大脑前动脉 磁共振血管造影术 超声检查 多普勒 经颅 

分 类 号：R743[医药卫生—神经病学与精神病学] R445.1[医药卫生—临床医学]