缓解期双相情感性精神障碍患者认知功能  

Cognitive function in remitted patients with bipolar affective mental disorder

作　　者：蔺华利[1] 施旺红[1] 雷莹[2] 

机构地区：[1]第四军医大学航空航天医学系心理教研室,西安710032 [2]西安市精神卫生中心

出　　处：《临床精神医学杂志》2006年第2期76-77,共2页Journal of Clinical Psychiatry

摘　　要：目的：了解缓解期双相情感性精神障碍患者认知功能损害的特点.方法：采用逻辑记忆、视觉再生记忆、连线测验A和B、数字广度测验、威斯康星卡片分类测验（WCST）及字色混淆测验（stroop）对62例缓解期双相情感性精神障碍患者（患者组）和62名健康者（对照组）进行有关言语学习和记忆、非言语学习和记忆、注意以及执行功能的神经心理学评定,比较两组间认知功能的差异.结果：患者组在即刻逻辑记忆、延迟逻辑记忆、连线测验A和B、WCST正确应答数、完成分类数、持续性错误数以及Stroop C-W操作分上均显著低于对照组（P＜0.05～0.01）.结论：双相情感性精神障碍患者的认知缺陷有其特点.Objective：To understand the cognitive function impairment in remitted patients with bipolar affective mental disorder. Method：Verbal learning and memory, nonverbal learning and memory, attention and executive function were assessed respectively with logical memory, visual reproduction, trail making test A and B, digit span subtest, WCST and strcop test in 62 remitted patients with bipolar affective mental disorder and 62 normal controls. Resuits：The perfomance of the patients on logical memory,trail making test A and B,WCST caregories,WCST correct, WCST perseveative errors and strcop C-W was significantly worse than those of normal controls（ P 〈 0.05 or 0. 01 ）. Conclusion： Cognitive deficits in remitted patients with bipolar affective mental disorder have some peculiarity.

关 键 词：缓解期双相情感性精神障碍 认知功能 神经心理测验 

分 类 号：R749.4[医药卫生—神经病学与精神病学]