Clinical characteristics of a group of adults with nodular lymphoid hyperplasia:A single center experience  

作　　者：Alberto Rubio-Tapia Jorge Hernández-Calleros Luis Uscanga Sagrario Trinidad-Hernández 

机构地区：[1]Department of Gastroenterology,Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran(INNSZ),Mexico City,Mexico [2]Department of Pathology,Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran(INNSZ),Mexico City,Mexico

出　　处：《World Journal of Gastroenterology》2006年第12期1945-1948,共4页世界胃肠病学杂志（英文版）

摘　　要：AIM： To describe the clinical and histological characteristics of a group of adults with small-bowel nodular lymphoid hyperplasia （NLH）. METHODS： Patients were searched for five years in pathology records of our institution. The biopsy material was reassessed using strict histopathological criteria. Clinical data were obtained from medical records. RESULTS： Small-bowel NLH was diagnosed in 18 cases. The female： male ratio was 2 ： 1. The most frequent symptoms were diarrhea （72%）, involuntary weight loss （72%） and abdominal pain （61%）. Nine patients （50%） had immunodeficiency. Small-bowel bacterial overgrowth was found in three （17%） cases. At small-bowel NLH diagnosis, three （17%） had associated lymphoma： two intestinal and one extra-intestinal lymphomas. In two patients with villous atrophy and anti-endomysial antibodies the diagnosis of celiac disease was established. Giardia larnblia infection was found in only one patient with hypogammaglobulinemia （Herman＇s syndrome）. CONCLUSIONS： NLH is uncommon in adult patients. Associated diseases are immunodeficiency and lymphoid tissue malignancies.瞄准：与小肠的榴状的淋巴的增生(NLH ) 描述一组成年人的临床、组织学的特征。方法：病人们在我们的机构的病理记录被在找五年。活体检视材料用严格的组织病理学说的标准被重估。临床的数据从医药记录被获得。结果：小肠的 NLH 在 18 种情况中被诊断。女性：男比率是 2:1。最经常的症状是腹泻(72%) ，非自愿的重量损失(72%) 和腹的疼痛(61%) 。九个病人(50%) 有免疫不全。小肠的细菌的增生在三被发现(17%) 盒子。在小肠的 NLH 诊断，(17%) 三联系了淋巴瘤：二肠并且一个额外肠的淋巴瘤。在有覆有一层绒毛的萎缩和 anti-endomysial 抗体的二个病人，乳糜泻的诊断被建立。兰伯氏贾第虫感染与 hypogammaglobulinemia (赫尔曼的症候群) 在仅仅一个病人被发现。结论：NLH 在成年病人是不平常的。联系疾病是免疫不全和淋巴组织恶意。

关 键 词：Nodular lymphoid hyperplasia HYPOGAMMAGLOBULINEMIA LYMPHOMA 

分 类 号：R574[医药卫生—消化系统]