软X线治疗皮肤基底细胞癌和鳞状细胞癌  

Soft x-ray therapy for cutaneous basal cell and squamous cell carcinomas

作　　者：Schulte K.-W. Lippold A. Auras C. L. Suter 崔荣 

机构地区：[1]In der Stroth 37, D-48157, M nster, Germany Dr

出　　处：《世界核心医学期刊文摘（皮肤病学分册）》2006年第3期11-12,共2页Digest of the World Core Medical JOurnals:Dermatology

摘　　要：Background: We have used a schedule for soft x-ray therapy of epithelial malignancies that takes into account the clinically diagnosed tumor involution under treatment. Objective: We sought to evaluate the effectiveness of this schedule in terms of cure rate and late ulcerations. Methods: Patients with 1267 consecutively irradiated (1988- 1992) basal cell and squamous cell carcinomas were followed up (average 77months). Results: The recurrence rate (5.1% ) was related to tumor size and thickness and to the time-dose-fractionation factor. The frequency of ulcerations (6.3% ) depended on field size, hardness of the x-rays, and in smaller fields (diameter up to 4 cm) on total dose, and time-dose-fractionation factor. Of all ulcerations, 82.5 % could be conservatively cured. Limitations: We have no evidence that our radiation schedule is superior to those published by other authors. Conclusion: These results verify theBackground： We have used a schedule for soft x-ray therapy of epithelial malignancies that takes into account the clinically diagnosed tumor involution under treatment. Objective： We sought to evaluate the effectiveness of this schedule in terms of cure rate and late ulcerations. Methods： Patients with 1267 consecutively irradiated （1988 - 1992） basal cell and squamous cell carcinomas were followed up （average 77months） . Results： The recurrence rate （5.1%） was related to tumor size and thickness and to the time-dose-fractionation factor. The frequency of ulcerations （6. 3% ） depended on field size, hardness of the x-rays, and in smaller fields （diameter up to 4 cm） on total dose, and time-dose-fractionation factor. Of all ulcerations, 82.5 % could be conservatively cured. Limitations： We have no evidence that our radiation schedule is superior to those published by other authors. Conclusion： These results verify the use.

关 键 词：皮肤基底细胞癌 鳞状细胞癌患者 X线治疗 恶性肿瘤 溃疡形成 剂量分次 肿瘤复发率 连续照射 照射剂量 文献报道 

分 类 号：R739.5[医药卫生—肿瘤] R735.1[医药卫生—临床医学]