Azone对沙土鼠软脑膜微循环的作用  

Effect of Azone on Pia Microcirculation in Gerbil

作　　者：吴云清[1] 薛全福[1] 康复安 梁秀敏[3] 李长平[3] 杨延松[3] 

机构地区：[1]中国医学科学院基础医学研究所 [2]北京市神经外科研究所 [3]防化研究院4所

出　　处：《微循环学杂志》1996年第1期15-17,共3页Chinese Journal of Microcirculation

摘　　要：观察Azone对沙土鼠软脑膜微循环通透荧光标记右旋糖酐的影响。发现无论在正常鼠或结扎双侧颈总动脉形成脑缺血鼠及脑缺血加用Milrinone(氰联吡啶酮)鼠,给Azone后,软脑膜微循环均有类似变化:血流速度加快,血流量增加,毛细血管通透性增加,沉积在血管壁上的荧光标记物被清除,且仅为程度不同。而单用Azone的溶剂丙二醇则无上述作用。Effect of Azone on Pia Microcirculation in gerbil was observed. Results showed that Azone application could increase the pia microcirculatory blood flow volume and pia capillary permeability to flurescene labelled Dextran in normal gerbil brain, isehemic gerbil brain induced by ligation of bilateral cervical artery and ischemie gerbil brain treated by Milrinone. Morever the flurescene labelled Dextran sticked on the wall of pia blood vessel could be cleared away as well.

关 键 词：微循环 脑膜微循环 AZONE 助渗剂 脑缺血 

分 类 号：R743.310.2[医药卫生—神经病学与精神病学] R944.9[医药卫生—临床医学]