镉对黑斑蛙脏器组织的亚慢性毒性效应  

Subchronic toxic effects of cadmium on the viscera tissues of the frog Rana nigromaculata

作　　者：贾秀英[1] 杨亚琴[1] 

机构地区：[1]杭州师范学院生命科学学院,浙江杭州310036

出　　处：《中国环境科学》2006年第2期228-232,共5页China Environmental Science

基　　金：浙江省自然科学基金资助项目(302056);浙江省动物学重点学科资助项目

摘　　要：研究了在不同浓度镉（10-40mg／L）中暴露30d 黑斑蛙（Rana nigromaculata）脏器组织的亚慢性毒性效应．结果表明，当镉暴露浓度〉30mg／L时，黑斑蛙的肝脏指数显著减少．黑斑蛙肝脏、肾脏和心脏Na^＋-K^＋-ATPase活性随着Cd^2＋浓度的升高而降低，表现出明显的浓度-效应关系．在同一浓度（20mg/L）不同时间处理中，肝脏、肾脏组织Na^＋-K^＋-ATPase活性随处理时间的延长表现为先升高后下降的趋势．肝脏和肾脏Na^＋-K^＋-ATPase对Cd^2＋更为敏感．肝脏指数的减少和肝脏、肾脏、心脏组织Na^＋-K^＋-ATPase活性的变化在一定程度上反映了镉对黑斑蛙的损伤作用．The subchronic toxic effects of Rana nigromaculata viscera tissues exposed 30d in different Cd^2＋ concentrations （10-40mg/L） were studied adopting toxial experiment technique. At the exposure concentration 〉30mg/L, the hepatosomatic index （HSI） of Rana nigromaculata decreased markedly. The Na^＋-K^＋-ATPase activities in the liver, kidney and heart decreased with Cd^2＋ concentration increased, expressing obvious concentration-effect relationship. In the treatment of same concentration （20mg/L） and different time, the Na^＋-K^＋-ATPase activities in the liver and kidney tissues tended to raise first and then declined, and there two tissues showed more sensitive on Cd^2＋. The decrease of HSI and the change of Na^＋-K^＋-ATPase activities of liver, kidney and heart reflected at definite degree the damage action of cadmium on Rana nigromaculata.

关 键 词：镉 黑斑蛙 肝脏指数 Na^+-K^+-ATPase活性 毒性效应 

分 类 号：X176[环境科学与工程—环境科学]