侵袭性血管粘液瘤的临床病理分析  

Clinicopathological Analysis of Aggressive Angiomyxoma

作　　者：任黔川[1] 彭芝兰[1] 

机构地区：[1]四川大学华西第二医院妇产科,四川成都610041

出　　处：《华西医学》2006年第2期261-262,共2页West China Medical Journal

摘　　要：目的研究侵袭性血管粘液瘤的临床特点与病理特征,以免误诊漏诊。方法对侵袭性血管粘液瘤3例行手术切除,并行光镜和免疫组化检查。结果术中见肿瘤呈无包膜生长,剖面苍白色、胶质样,有粘液性间质分隔。病检示瘤细胞呈梭形或星形排列于粘液样背景中,核无异型性或分裂相,其间有中等以上厚壁血管。免疫组化染色示Vimentin(+)、S-100(-)。结论侵袭性血管粘液瘤罕见,侵袭性与复发性是其重要的临床特点。治疗以扩大的局部切除为宜,并需长期随访。Ohjective： To study the clinical and pathological characteristics of the aggressive angiomyxoma of the vulva for avoiding misdignosis or missing of the diagnosis. Method： A detailed clinicopathotogieal analysis was performed on two patients with aggressive angiomyxoma ＇after operations. Results： The tumor grossty was without capsulation, and segregated by myxoid stroma. The cut surface showed a soft, grayish white and colloid. Histologically, the tumour was composed of spinde or stellate shard cells in the myxoid stroma with mediumsized thick walled vessels. There was no nuclear atypia or mitotic activity. Immunohistochemically, vimentin was positive and S100 protein was negative. Conclusion： Aggressive angiomyxoma is a distinctive and rare soft tissue tumour. It was important that the infiltrating range of tumour should be understood before opperation. The reconunended treatment of aggressive angiomyxoma of the vulva was local excision with wide free margin and long term follow up was needed.

关 键 词：血管粘液瘤 软组织肿瘤 病理学 临床 

分 类 号：R737.3[医药卫生—肿瘤]