食管裂孔疝伴胃食管反流病的胃食管动力学研究  

Gastroesophageal Motility in Patients with Sliding Hiatus Hernia and Gastroesophageal Reflux Disease

作　　者：赵贵君 霍江波 栗鹏 梁国士 

机构地区：[1]内蒙古消化病研究所,内蒙古包头014030

出　　处：《包头医学院学报》2006年第1期1-3,共3页Journal of Baotou Medical College

摘　　要：目的:探讨食管裂孔疝(HH)伴胃食管反流病(GERD)患者与单纯HH及GERD患者之间的内镜、24h食管pH监测、食管测压、胃动力学检查之间的相关性。方法:经胃镜确诊的HH伴GERD患者61例,同期内镜确诊单纯HH患者28例,GERD患者30例,在一周内进行24h食管pH监测、食管下端括约肌(LES)压力测定及胃磁图测定胃半排空时间。结果:GERD中pH监测诊断同内镜诊断相符合占83.52%,不符合占16.48%。24h pH监测中,HH伴GERD组患者的总反流时间、卧位反流时间及立位反流时间百分比均显著高于GERD组和HH组,GERD组显著高于HH组;HH伴GERD组LESP显著低于HH组和GERD组,HH组LESP显著低于GERD组;HH伴GERD组LESL显著短于GERD组,HH伴GERD组和HH组LESL无显著差异,HH组LESL显著短于GERD组;HH伴GERD组LESR显著高于HH组和GERD组,HH组LESR显著高于GERD组;HH伴GERD组胃排空延缓者显著多于HH组,但与GERD组无显著差异,GERD组胃排空延缓者显著多于HH组。Objective： To study changes in gastroesophageal motility of patients with sliding hiatus hernia （HH） and gastroesophageal reflux disease. Methods： 61 HH＆GERD patients, 28 HH patients and 30 GERD patients were diagnosed with gastroscopy to monitor 24 - hour esophageal pH and to determine gastric half - emptying time with gastromagneticgram, and the lower esophagea/sphincter （LES） pressure. Rosults： Among GERD, the percentage of pH monitoring diagnosis conforming to gastroesophageal diagnosis is 83.52%, 16. 48% does not conform to gastroeo - phageal diagnosis During 24 - hour esophageal pH monitoring, the percentages of total, supine and upright acid exposure time of HH＆ GERD group are greater than those in GERD group and HH group. （ Percentages of upright acid exposure time of HH＆ GERD group and upright acid exposure time of GERD group are P 〈 0. 05. Others are P 〈 0, 01 ） GERD group is higher than HH group remarkably （ P 〈 0. 05 ）. LESP in HH＆GERD group is lower than that in HH group and GERD group （P〈0. 01）. LESP in HH group is lower than that in GERD group （P 〈 0, 01 ）, LESL in HH＆GERD group is shorter than that in GERD group （ P 〈 0. 01 ）. LESL in HH＆GERD group shows no significant differences from LESL in HH group. LESL in HH group is shorter than that in GERD group （ P 〈 0. 01 ）. LESR in HH＆GERD group is higher than that LESRin HH group and in GERD group （ P 〈0. 01 ）. LESR in HH group is higher than that in GERD group （P 〈0.01 ）. Patients of gastric emptying delay in HH＆GERD group are much more than those in HH group （P 〈 0, 01 ）, Patients of gastric emptying delay in HH＆GERD group show no significant differences from those in GERD group. Patients of gastric emptying delay in GERD group are much more than patients in HH group （P〈0.01）.

关 键 词：疝 食管裂孔 胃食管反流 内镜 PH监测 测压法 胃磁图 

分 类 号：R571[医药卫生—消化系统]