宫颈癌腔内放射治疗的三维剂量分布验证  

Detection of 3D-dose distribution of intracavitary brachytherapy for cervical cancer patients

作　　者：徐海荣[1] 张书旭[1] 李文华[1] 

机构地区：[1]广州南方医科大学生物医学工程学院,广东广州510515

出　　处：《第四军医大学学报》2006年第9期796-798,共3页Journal of the Fourth Military Medical University

基　　金：广东省自然科学基金(37065);广东省科技计划项目(C30601)

摘　　要：目的:采用成都仿真人体盆腔模型及LIF(Mg.Cu.P)热释光剂量计(TLD)验证宫颈癌腔内后装治疗三维剂量分布的可行性.方法:根据临床腔内后装放射治疗模拟计划方案,在仿真人体盆腔模型内设置参考点(孔),把TLD元件放入仿真人体盆腔模型测试孔内,用MicroSelectronHDR后装治疗机按模拟计划设计进行腔内照射,FJ427A1热释光剂量仪对受照后TLD元件进行重复测量,比较计算值和测量值的差异.结果:本次采用的TLD元件剂量线性好,A,B,F点、膀胱和直肠剂量参考点实测剂量与3DVTPS计算值符合较好,其平均误差在±5.16%.结论:TLD实测剂量能较好的反应患者的实际受照剂量,对预测放疗副作用、优化放疗计划、提高疗效有重要价值.AIM： To investigate the feasibility of checking the 3D-dose distributions of intracavitary brachytherapy for cervical cancer patients by thermoluminescent dosimeter （TLD） [ LIF （Mg. Cu. P ）] in an anthropomorphic pelvic phantom. METHODS： On the basis of a simulated intracavitary brachytherapy plan, TLD components were put into test holes in anthropomorphic pelvic phantom for measuring the dose to each TLD component with FJg27-A1 dosimeter following the intracavitary irradiation with MicroSelectron HDR afterloader at the prescription dose. The measured values were compared with the calculated ones. RESULTS： A good linear relationship was found between the TLD components＇ measured values and the irradiation doses within the range of 0 - 300 cGy, and the former ones were in a good line with the calculated ones with 3DV-TPS at the reference points of A, B, F, bladder and rectal doses, average error being ±5.16%. CONCLUSION： TLD components＇ tested doses can well reflect the exposure doses of patients, so it is of important value to forecast radiotherapy side effects, optimize radiotherapy plan and improve curative effect.

关 键 词：宫颈肿瘤 放射疗法 热释光剂量计 

分 类 号：R737.33[医药卫生—肿瘤] R730.55[医药卫生—临床医学]