人食管鳞癌细胞及癌旁细胞流式细胞光度术分析  

Flow Cytometric Analysis of Cellular DNA Content and Cell Cycle of Pert-Cancer Tissues and Cancer Tissues in the Carcinoma of the Esophagus

作　　者：丁蔚[1] 银德仁[1] 张娓[1] 白经修[1] 丁明杰[1] 杨巧红[1] 王英华[1] 

机构地区：[1]河南医科大学组织学与胚胎学教研室,新乡市中心医院病理科,河南医科大学第二附属医院手术室

出　　处：《河南肿瘤学杂志》1996年第4期241-243,共3页Henan Journal of Oncology

摘　　要：本研究应用流式细胞光度术对１４例人食管鳞癌手术切除标本的癌、癌旁组织和正常食管上皮细胞进行细胞动力学和细胞ＤＮＡ含量分析。结果表明；处于Ｓ期癌细胞的数量明显高于癌旁细胞和正常食管上皮细胞；癌细胞ＤＩ值明显高于癌旁细胞。因此，应用流式细胞光度术作癌和癌旁细胞核的ＤＮＡ分析，对于食管鳞癌的临床诊断有一定的帮助。Cellular DNA content and cell cycle of espohageal epithelium,peri-cancer tissues and cancer tissues in the carcinoma of the esophagus were analyzed by Flow Cytometry(FCM).The results showed that the ratios of cell number in S phases in cancer group were significantly higher than that of pert-cancer group and that of normal esophageal epithelium group,respectively.The value of DNA index in cancer group was significantly higher than that in pert-cancer group.Therefore,cancer cellular DNA content measured by FCM was conducive to clinical diagnosis.

关 键 词：食管鳞癌 DNA指数 流式细胞光度术 

分 类 号：R735.1[医药卫生—肿瘤]