乳腺癌术前灌注化疗与肿瘤供血的研究  

Preoperative Chemotherapeutic Infusion and Blood Supply in Breast Cancer

作　　者：梁立华[1] 陈义雄[1] 唐震[1] 周国英[1] 夏宁[1] 刁胜林[1] 

机构地区：[1]广东医学院附属医院

出　　处：《临床放射学杂志》1996年第3期182-183,共2页Journal of Clinical Radiology

摘　　要：目的：通过对乳腺癌肿瘤血供的研究，为动脉灌注化疗奠定基础。材料与方法：６例乳腺癌患者，采用Ｓｅｌｄｉｎｇｅｒ技术，行锁骨下动脉造影，然后选择性动脉内灌注ＡＤＭ６０ｍｇ，ＣＤＤＰ８０ｍｇ，ＭＭＣ１２～１８ｍｇ。结果：（１）肿瘤主要血供５０％来自胸廓外侧动脉，肩胛下动脉及胸廓内动脉各占２５％，与以往观点不同；（２）６例乳腺癌经动脉灌注后原发灶及淋巴结均明显缩小。结论：乳腺癌的供血主要是胸廓外侧动脉，其次为肩胛下动脉及胸廓内动脉。作者提出行动脉灌注化疗时，不宜只行胸廓内动脉，而应以上３支动脉一起灌注。Objective: Blood supply of breast carcinoma was studied for arterial chemotherapeutics infusion.Materials and Methods: The Seldinger's techniques and subscapularis arteriography were taken. Then selective arterial infusion with ADM 60mg, CDDP 80mg and MMC 12～18mg were performed.Results: (1) 50 percent of blood supplies of the tumors were from the thoracica lateralis artery, 25 percent from subscapularis and 25 percent from thoracica internal artery, which was different from old opinions; (2) The tumors and lymph nodes became small in all cases through artery infusion.Conclusion: Blood supply of breast carcinoma is from thoracica lateralis artery mainly. It consider that: when arterial infusion of chemicals is performed, it should be taken in the three arteries instead of thoracica lateralis artery. Only that, better effects can be obtained.

关 键 词：乳腺癌 肿瘤血供 药物疗法 

分 类 号：R737.905[医药卫生—肿瘤]