恶性肿瘤患者血清唾液酸含量的改变  

THE CHANGE OF SIALIC ACID CONTENT IN THE SERUM OF PATIENTS WITH MALIGNANT TUMOURS

作　　者：李和楼[1] 孟广琴[1] 王君林[1] 

机构地区：[1]泰山医学院附属医院,山东省泰安市泰山区人民医院

出　　处：《肿瘤研究与临床》1996年第2期79-81,共3页Cancer Research and Clinic

摘　　要：报告５０例正常人及１３２例恶性肿瘤患者血清唾液酸的含量，其结果是正常人为１．６４±０．１８ｍｍｏｌ／Ｌ，４０例肺癌患者为２．６４±０．４３ｍｍｏｌ／Ｌ，阳性率为９２．５％；１８例食管癌患者２．５５±０．４３ｍｍｏｌ／Ｌ阳性率为８３．３％；２２例胃癌患者为２，３８±０．３７ｍｍｏｌ／Ｌ阳性率为８１．８％；１６例妇科恶性肿瘤患者为２．６０±０．４４ｍｍｏｌ／Ｌ，阳性率为８１．３％；８例直肠癌患者为２．５９±０．４１ｍｍｏｌ／Ｌ阳性率为７５．０％；１０例肝癌患者为２．６０±０．４２ｍｍｏｌ／Ｌ阳性率为７０．０％；各种恶性肿瘤患者与正常人比较均有极显著差异（Ｐ＜０．００ｌ）。观察了部分恶性肿瘤患者手术前后的唾液改变化。The sialic acid contents in the serum of 50 normal controls and 124 patients withmalignant tumours was reported, The result was as follows:in normal controls it was l.64±0.18 mmol/L;in 4O patients with pulmonary cancer it was 2.64±0.4 3 mmol/L,and thepoitive rate was 92.5%,in l8 patients with esophgeal carcinoma,2.55 ± 0.43 mmol/Land83.3%;in 22 patients with gastric carcinoma,2.38±0.37 mmol/L and 81.8%;in 16 patientswith gynecologic nialignant tumour,2.60± 0.44 mmol/L and 81.3%;in 8 patients with rectalcarcinoma,2.59±0.4I mmol/L and 70.0%. The differences bctwcen normal controls andpatiet1ts with various kinds of fnalignant tumours was extremely significant(P<0.0l).We alsohave observed the sialic acid chaiige in some of the patients with malignant tumours post-operatively.

关 键 词：恶性肿瘤 唾液酸 血清 

分 类 号：R730.2[医药卫生—肿瘤]