放射治疗结合热疗治疗宫颈癌的疗效观察  

The Effect of Radiotherapy Combined with Hyperthermia for Cervix Carcinoma

作　　者：沈湘[1] 余忠华[1] 梁荣[1] 刘付冬[1] 

机构地区：[1]广东医学院附属医院肿瘤放疗科,广东湛江524001

出　　处：《四川肿瘤防治》2006年第2期92-94,共3页Sichuan Journal of Cancer Control

摘　　要：目的:观察放射治疗加热疗治疗宫颈癌的临床效果。方法:将66例经病理确诊的宫颈癌患者随机分为两组:放射治疗+热疗组(热放组)33例和单纯放射治疗组(单放组)33例。两组的放射治疗方法一样:全盆照射+盆腔四野照射+腔内后装放疗。热放组采用了射频深部热疗和微波腔内热疗,热疗每周1次至2次,直至放疗结束。每次热疗均在放疗后30分钟内开始。结果:热放组和单放组的局部控制率(CR)分别为84．8％和 60．6％,有显著性差异(P<0．05)。1年、2年的生存率两组无显著差异(P>0．05),但3年生存率分别为84．8％和 63．6％,有着显著性差异(P<0．05)。结论:放射治疗结合热疗可提高宫颈癌患者的局部控制率和生存率。Objective： To determine the efficacy of radiotherapy combined with hyperthermia for cervix carcinoma. Methods： 66 eases of cervix carcinoma diagnosed by pathology were divided randomly into two groups： 33 patients treated with radiotherapy plus hyperthermia （H ＋R group）; 33 patients treated with radiotherapy alone （R group）. Radiotherapies of both groups were alike： pelvic external irradiation plus intracavitary brachytherapy. H ＋ R group was treated with hyperthermia, which was given 30 minutes after radiotherapy＇, once or twice per week, until radiotherapy was over. Results： The local control rates of H ＋ R group and R group were 84. 8% and 60. 6% （P 〈 0. 05） respectively. The 3-year survival rates of H ＋ R group and R group were 84. 8% and 63.6% （P 〈0. 05） respectively, though there was no statistical significance in the 1-year and 2-year survival rates. Conclusion： Radiotherapy combined with hyperthermia is instrumental in raising the local control rate and survival rate for the patients with cervix carcinoma.

关 键 词：宫颈癌 放射治疗 热疗 预后 

分 类 号：R737.33[医药卫生—肿瘤] R730.55[医药卫生—临床医学]