23例晚期胰腺癌三维适形放疗的疗效评价  

Evaluation of Three-Dimensional Conformal Radiotherapy for Locally Advanced Pancreatic Carcinoma

作　　者：谭燕[1] 付彬玉[1] 张伟[1] 李柏森[1] 何毅[2] 

机构地区：[1]四川省肿瘤医院放疗科,四川成都610041 [2]重庆医科大学卫生学校,重庆400016

出　　处：《四川肿瘤防治》2006年第2期120-121,128,共3页Sichuan Journal of Cancer Control

摘　　要：目的:探讨三维适形放射治疗晚期胰腺癌的疗效。方法:23例晚期胰腺癌患者采用三维适形放射治疗,总量DT 60Gy-66Gy,分30次-33次,6周-7周内完成。结果:23例患者经放疗后1个月-3个月,经CT、 MRI复查肿瘤局部缓解率(CR+PR)为:69．5％(16/23)。其中1例完全缓解,15例部分缓解。疼痛控制率(CR+ PR)为:83％(19/23)。1、2年生成率分别为:56．5％(13/23)、17％(3/23)中位生存期12．5个月。放疗副反应可以耐受。结论:三维适形放疗是晚期胰腺癌治疗的一种安全有效的姑息治疗手段。Objective： To evaluate the efficacy of three-dimensional conformal radiotherapy（3D-CRT） on locally advanced pancreatic carcinoma. Methods： From May 2001 to July 2003, 23 patients with locally advanced pancreatic carcinoma received 3D- CRT. The total dose was 60Gy ～ 66Gy, given in 30～33 fractions, completed in 6～ 7 weeks. Results： The overall response was 69.5% （ 1 complete response, 15 partial reponse）. The rate of partial and complete pain relief was 83%. The 1-years and 2-year survival rate were 56. 5% and 17% respectively. The median survival time was 12. 5 months. The main acute radiation reation was mild nausea. Conclusion： 3D-CRT is an effective and safe method for locally advanced pancreatic carcinoma.

关 键 词：胰腺癌 三维适形放疗 疗效 

分 类 号：R735.9[医药卫生—肿瘤]