幽门螺旋杆菌感染上消化道疾病的关系  

The Relationship between Infection of HP and Disease of Upper Digestive Tract.

作　　者：徐慧[1] 武斌[1] 

机构地区：[1]延安大学医学院2001级1班,陕西西安716000

出　　处：《中国现代医药杂志》2006年第3期7-8,共2页Modern Medicine Journal of China

摘　　要：目的研究幽门螺旋杆菌(HP)与上消化道疾病的关系。方法选择1836例上消化道不适且经Olympus胃镜检查胃黏膜直接涂片革兰氏染色镜检HP和快速尿素酶试验检测为阳性即确定为幽门螺旋杆菌感染的患者为研究对象,随机选取353例来院检查未查出上消化道疾病的为对照组。结果上消化道疾病HP感染阳性率为63.0%,其中食管癌63.9%,贲门癌66.7%,胃癌72.9%,消化性溃疡73.6%,慢性萎缩性胃炎61.2%,浅表性胃炎60.9%;农村患者的总检出率为85.5%,城市患者为36.6%,农村明显高于城市。上消化道不同部位溃疡的HP检出率除幽门口溃疡为68.8%外,其他均高于70%,对照组HP阳性率为14.6%。结论上消化道疾病与HP感染密切相关,农村人口感染率明显高于城市。Objective To study the relationship between infection of helicobacter pylori （HP） and disease of upper digestive tract. Methods 1836 patients, who suffered from upper digestive tract upset and their biopsy samples had been confinned Gram＇s stain and positive of urease test, were selected in laboratory group, and 353 cases without upper digestive tract upset were selected in control group.Results The positive infection rate of HP in upper digestive tract was 63.0%. Among them, the positive rates of HP in esophageal carcinoma, carcinoma of gastric cardia, gastric cancer, peptic ulcer, chronic atrophic gastritis, superficial gastritis were 63.9%, 66.7%, 72.9%, 73.6%, 61.2%, 60.9%, respectively. The rate of HP infection in rural （85.5%）, was higher in that of urban （36.6%）, and positive rate of HP was more than 70% in different patients with peptic ulcer except pylorus ulcer （68.8%） and only 14.6% in controls.Conclusion The infection of HP is associated with disease of upper digestive tract, and it is more common in rural than urban.

关 键 词：幽门螺旋杆菌感染 上消化道疾病 幽门螺旋杆菌 涂片革兰氏染色镜检 快速尿素酶试验 HP检出率 农村患者 胃镜检查 HP感染 

分 类 号：R57[医药卫生—消化系统]