三种纳米载银无机抗菌剂对口腔致病菌的抗菌活性比较  

Comparison of the antibacterial activity on oral pathogens among three types of nano-silver base inorganic antibacterial agents

作　　者：张林祺[1] 高勃[2] 杨聚才[1] 杜岩[1] 周冰[1] 

机构地区：[1]第四军医大学口腔医学院,陕西西安710032 [2]第四军医大学口腔医学院修复科,陕西西安710032

出　　处：《牙体牙髓牙周病学杂志》2006年第5期254-256,共3页Chinese Journal of Conservative Dentistry

摘　　要：目的:比较3种国内纳米级载银无机抗菌剂对口腔病原菌的抗菌活性。方法:采用微量板液体稀释法.测定GKJ-R、Conval PAg-40、TiO2/Ag3种纳米级载银无机抗菌剂对变形链球菌(ATCC25135)、乳酸杆菌(ATCC393)、黏性放线菌(ATCC19246)、牙龈卟啉单胞菌(ATCC33277)的最小杀菌浓度(MBC)。结果:3种纳米级载银无机抗菌剂对变形链球菌、乳酸杆菌、黏性放线菌、牙龈卟啉单胞菌均有良好的杀菌效果,且抗菌能力没有显著区别。结论:为纳米载银无机抗菌剂在牙科抗菌材料领域应用提供理论依据。AIM：To Compare the antibacterial activity on oral pathogens among three types of nano - silver base inorganic antibacterial agents. METHODS ：The oral pathogens selected were Streptococcus mutans（ ATCC25135 ） , Lactobacillus（ ATCC393 ） ,Actinomyces viscosus （ ATCC19246 ）, Candida Albicans （ ATCC33277 ）. Minimal bactericidal concentration （MBC）was determined by liquid dilution method. RESULTS ： Nano -silver base inorganic antibacterial agents had bactericidal activity against oral pathogens. The general antibacterial activity was nearly equal. CONCLUSION：It is possible that nano- silver base inorganic antibacterial agents can be used in dental antibacterial materials.

关 键 词：纳米级载银无机抗菌剂 口腔病原菌 抗菌活性 

分 类 号：R780.2[医药卫生—口腔医学]