消化道原发性淋巴瘤36例临床病理分析  

Pathological characteristics of primary gastrointestinal lymphoma

作　　者：刘志芳[1] 许云凤[1] 张伟伟[1] 

机构地区：[1]山东省莱州市人民医院病理科,261400

出　　处：《中华腹部疾病杂志》2006年第5期326-328,共3页Chinese Journal of Celiopathy

摘　　要：目的 探讨原发性消化道淋巴瘤的临床病理特点、诊断及鉴别诊断。方法对36例病理诊断为消化道原发性淋巴瘤。的病例临床资料、免疫组化进行回顾性分析研究。结果发生在胃部20例（56％），肠道13例（36％），阑尾3例（8％）。溃疡型13例（36%），浸润型15例（42％），结节型8例（22％）。36例中黏膜相关淋巴瘤（MALT）26例（72％），弥漫性大B细胞淋巴瘤（DLBCL）8例（22％），肠型T细胞淋巴瘤2例（6％）。结论消化道淋巴瘤临床缺乏特异性，内镜活检易漏诊或误诊为癌。明确组织学分型有助于选择治疗方案，发生在消化道MALT淋巴瘤病变局限，不累及淋巴结或其它组织器官，术后辅以化疗或放疗预后较好、多数可以长期存活。AIM To investigate the pathological characteristics and diagnosis of primary gastrointestinal lymphoma. METHODS Clinical records of 36 patients with primary gastrointestinal lymphoma were analysed, retrospectively. RESULTS Gastric lymphoma accounted for the. largest proportion of the patients, 56% （20/36） ,followed by intestinal and appendicular lymphoma,36. 1% and 8. 3%, respectively. Of all the lymphornas,36% were ulcerative,42% were infiltrating and 22% were nodular. Histopathological examination revealed that most patients （72%） had mucosa associated lymphoid tissue （MALT） lymphoma. CONCLUSIONS Primary gastrointestinal lymphema is often misdiagnosed under endoscopic biopsy pathology due to its unspecific histopathological presentations.

关 键 词：消化道 淋巴瘤 免疫组织化学 

分 类 号：R730.263[医药卫生—肿瘤]