经蝶入路显微切除垂体巨、大型腺瘤的策略与技巧  

The Surgical Strategies and Techniques of Transsphenoidal Microsurgery for Large and Giant Pituitary Adenomas

作　　者：陈明振[1] 

机构地区：[1]中山大学附属第三医院脑垂体瘤诊治研究中心,广东广州510630

出　　处：《中国神经肿瘤杂志》2006年第1期10-13,共4页Chinese Journal of Neuro-Oncology

摘　　要：背景与目的:垂体巨、大腺瘤是否采用经蝶手术尚有不同看法,本文总结垂体瘤手术经验,探讨经蝶入路显微切除垂体巨、大型腺瘤的理论依据、策略与技巧。方法:回顾性总结中山大学第一、第三医院收治垂体瘤的临床资料,对300例开颅术和1 110例经蝶手术疗效(分三个阶段)进行对比,重点讨论经蝶手术的策略和技巧。结果:经蝶切除垂体巨、大型腺瘤全切除率高,合并症少,生活质量好。结论:经蝶显微切除垂体大、巨大型腺瘤仍是最安全有效的首次和再次手术的首选方法。BACKGROUND ＆ OBJECTIVE： Treatment for giant as well as large pituitary adenomas has been a challenge. In this article, we are investigating the strategies and techniques of transsphenoidal mierosurgery for large and gaint pituitary adenomas. METHODS： Retrospective study was performed by comparing clinical data of 300 cases of eraniotomy versus 1 110 cases of transsphenoidal mieroneurosurgery for treatment of large and gaint pituitary adenomas. RESULTS： The total resection rate of transsphenoidal mierosurgery for pituitary giant- and maero-adenoma was high and complications were lower, and the quality of life of the patients was better as compared with patient treated with eraniotomy. CONCLUSIONS： Transsphenoidal mieroneurosurgery is an effective and safe choice for large and giant pituitary adenomas.

关 键 词：垂体腺瘤 经蝶入路 显微外科 

分 类 号：R739.41[医药卫生—肿瘤]