晚期食管癌食管内支架置入、动脉插管灌注化疗分析  

Metal stent combined with arterial intubation chemotherapy for advanced esophageal carcinoma

作　　者：张万高[1] 雷金生[1] 张玉梅[1] 

机构地区：[1]淮南矿业集团第四矿工医院介入科,安徽淮南232082

出　　处：《蚌埠医学院学报》2006年第3期290-292,共3页Journal of Bengbu Medical College

摘　　要：目的：观察联合运用食管内支架及动脉插管灌注化疗对晚期食管癌的疗效。方法：透视下定位经口放置自膨式覆膜镍钛合金内支架治疗食管狭窄19例；待患者体质恢复1～2周后，采用Seldinger技术，依肿瘤所在部位分别选择相应的供血动脉插管和造影，根据造影结果选择靶动脉灌注化疗药物。结果：19例共置入21根内支架，食管癌内支架置入后全部显效或有效；动脉灌注化疗显效4例，有效11例，无效3例，1例化疗1次后失访，总有效率78．9％，未见严重并发症发生。结论：食管内支架置入术治疗晚期食管癌的近期疗效肯定，结合动脉内灌注化疗两种技术联合运用可提高远期疗效及生活质量。Objective：To study the efficacy of metal stent combined with arterial intubation chemotherapy for treatment of advanced esophageal carcinoma. Methods： The self-expandlng Ni-Ti memorized alloy stent was placed though the mouth of 19 patients with advanced esophageal carcinoma under fluoroscopic guidance. When the physical condition of the patients recovered 1 -2 weeks later, selective arterial intubation chemotherapy was given to the location of the carcinoma with Seldinger method. Results：Twenty-one stents were used in 19 cases. Significant efficacy was obtained in all the patients. Effective arterial intubation chemotherapy was obtained in 4 cases,striking improvement in 11 cases and no response in 3 cases. One was out of contact after the first treatment. The total efficacy rate was 78.9%, with no severe complications. Conclusions：The metal stent for advanced esophageal carcinoma has certain efficacy in near future and can improve the long-term efficacy and the life quality of the patients when combined with arterial intubation chemotherapy

关 键 词：食管肿瘤 金属内支架 灌注法 局部 介入放射学 

分 类 号：R735.1[医药卫生—肿瘤]