晚期青光眼视网膜超微结构的观察  

An ultrastructural study on human retina with late glaucoma

作　　者：孙芳娥[1] 张希兰[1] 卞晓云 宋秀君[1] 

机构地区：[1]河北医科大学第三医院眼科,石家庄050051

出　　处：《中华眼科杂志》1996年第1期35-37,共3页Chinese Journal of Ophthalmology

摘　　要：目的为研究青光眼视网膜的病理改变。方法用透射电镜观察了6例(6只眼)晚期青光眼的视网膜超微结构的改变。结果发现视网膜神经纤维层明显变薄,轴突严重破坏并丧失,神经节细胞几乎消失,可见大量细胞样体。视网膜内、外核层神经细胞数目减少、变性、排列紊乱,视杆、视锥细胞外节变性水肿。结论提示青光眼的病理改变主要是神经节细胞及其轴突变性、萎缩。这些病理改变导致青光眼视功能永久性损害。Objective To study the pathologic changes of retina in glaucoma.Method Retinas from 6 cases with absolute glaucoma were observed by transmission electron microscope.Result It was found that the nerve fiber layer was significantly thin and the axons were severely damaged even lost; the ganglion cells nearly disappeared and a number of cell-like bodies were seen instead;the nerve cells of the outer and inner nuclear layers were degenerated,decreased in number,and disorderly arranged; the outer segments of the cone and rod cells became degenerative and edematous.Conclusion In ad- vanced glaucoma the degeneration and atrophy of the ganglion cells and their nerve axons were the major pathologic changes of the retina that lead to the permanent damage of visual function.

关 键 词：青光眼 视网膜 超微结构 

分 类 号：R775.02[医药卫生—眼科]