甲状腺动脉栓塞治疗难治性青少年Graves'病的临床研究  

Clinical study of arterial embolotherapy on refratory Graves' diease with adolescents patients

作　　者：徐玲[1] 徐勇[1] 干锦华[1] 蒋岚[1] 马红艳[1] 李春林[1] 钟海花[1] 

机构地区：[1]四川泸州医学院附属医院内分泌科,四川泸州646000

出　　处：《中国现代医学杂志》2006年第10期1544-1546,共3页China Journal of Modern Medicine

摘　　要：目的对难治性青少年Graves'病患者采用甲状腺动脉栓塞治疗,评价该方法的有效性、安全性及不良反应。方法对17例青少年Graves'病患者经股动脉插管至双侧甲状腺上动脉和/或一侧下动脉并注入栓塞剂聚乙烯醇(PVA),观察术后患者症状,体征及甲状腺功能等的变化。结果甲状腺在术后1～3d开始缩小,12例甲状腺缩小至Ⅰ度或正常大小;术后1个月甲状腺激素水平均下降,5例患者停用抗甲状腺功能亢进症(简称甲亢)药。结论介入栓塞治疗难治性青少年Graves'病安全、简便,近、中期疗效肯定。[Objective] To evaluate clinical application of arterial embolotherapy on refratory hyperthyroidism in adolescents. [Methods] Superselective arteriography and interventional embolization of thyroid superior and （or） inferior arteries were performed with PVA in 17 cases adolescents patients of refractory graves disease. The symptoms, signs and the level of T3 and T4 were observed after treatment. [Results] The procedures were succeeded in all patients. 24-72 hours after the embolotherapy, the size of thyroid gland was decreased in all patients. Following 1 year, the thyroid function of all pations were gradually come to normal, 5 patients needn＇t antithyroid drug and achived complete remission. No serous complications occurred. [Conclusions] Arterial embolotherapy is a safe, simple, reliable and effective treatment for refractory graves disease in adolescents.

关 键 词：青少年 Graves’病 动脉栓塞 

分 类 号：R581[医药卫生—内分泌]