急性淋巴细胞白血病细胞表面阴离子位点的研究  

Study of the Anionic Sites on the Surface of Cells in Acute Lymphoblastic Leukemia

作　　者：李晓林[1] 解勤芝[1] 周军[2] 严文保[2] 文建国[2] 

机构地区：[1]湖南医科大学湘雅医院血液科,410008 [2]湖南医科大学组织胚胎学教研室

出　　处：《临床血液学杂志》1996年第1期15-17,共3页Journal of Clinical Hematology

摘　　要：对急性淋巴细胞白血病(ALL)细胞表面阴离子分布进行了研究,以聚乙稀亚胺(PEI)作为阳离子示踪剂显示其阴离子——即阴离子位点.观察发现,ALL细胞表面阴离子位点密度较正常组为大,分布不规则,图象分析显示平均灰度值、积分光密度增高,ALL缓解患者细胞表面阴离子位点反应明显减弱,与正常组比较差异无显著性,提示ALL细胞阴离子位点增加与细胞恶性分化有关.the anionic sites at the surface of cell acute lymphoblastic leukemia (ALL)were investigated by using a ontionic-polyethyleneimine(PEI) ,and were measuredusing image analysis. It was showed that the anionic sites at the surface of lymphoblast in ALL are higher than those of normal and buffer cases and are not unified,The results indicated that the changes of the anionic sites in ALL have correlation with abnormal differetiated of leukemia.

关 键 词：白血病 聚乙烯亚胺 阴离子位点 图象分析 

分 类 号：R733.71[医药卫生—肿瘤]