中药联合化疗治疗晚期原发性非小细胞肺癌疗效分析  

Study on therapeutic effect of Chinese herbs combined with chemotherapy on advanced non-small cell lung cancer

作　　者：苏晋梅[1] 韩明权[1] 黄海茵[1] 龙为红[1] 秦丽萍[1] 

机构地区：[1]同济大学附属上海市肺科医院,上海200433

出　　处：《临床医药实践》2006年第6期409-411,共3页Proceeding of Clinical Medicine

摘　　要：目的:探讨中西医结合对晚期非小细胞肺癌的治疗作用。方法:对68例晚期非小细胞肺癌患者给予中药辨证论治加化疗治疗(中西组,第Ⅰ组),并与51例单纯化疗(化疗组,第Ⅱ组)比较。中药辨证论治分为气虚痰湿型、气阴两虚型、阴虚内热型和痰阻血瘀型。结果:两组近期客观疗效相近,两组有效率(CR+PR)分别为45.6%,33.3%(P>0.05),但中西组的稳定率(CR+PR+NC)为79.4%,明显高于化疗组56.9%(P<0.01)。化疗后中西组患者生活质量评分明显高于化疗组(P<0.05),中位生存期中西组为10.6个月,化疗组为8.4个月。结论:中医辨证论治加化疗可提高晚期非小细胞肺癌患者的稳定率,改善生活质量,但中药与化疗结合并未能明显提高治疗有效率及远期生存率。To observe the effect of traditional Chinese medicinal herbs combined with systemic chemotherapy on advanced non-small cell lung caneer（NSCLC）. Methods ：From May 2001 to December 2003,119 patients with advanced NSCLC were divided at random into two groups ：group Ⅰ ,68 eases treated with traditional Chinese medicine combination with systemic chemotherapy,group Ⅱ ,51 cases treated with systemic chemotherapy alone. The protocol of chemotherapy used in the two groups was similar. Results：Effective rats（CR＋PR） were 45.6% in group Ⅰ ,33.3% in group Ⅱ . There were no significant differences between these two groups according to the short term results（P〉0.05）. Mean survival time（month）for group Ⅰ and group Ⅱ were 10.6 and 8.4 respectively. Stabi lize rates （CR ＋PR＋ NC）（79.4 % ） of group Ⅰ was significantly higher than that of group Ⅱ （56.9% ）（P〈20.01）. Living quality of group Ⅰ was significantly higher than that of group Ⅱ （P〈0. 01）. Conclusions ：Chinese medicinal herbs combined with systemic chemotherapy were helpful to improve stabilize rates and living quality, However Chinese medicinal herbs combined with systemic chemotherapy did not improve the effective rats and survival rats.

关 键 词：非小细胞肺癌 中医药 辨证论治 化疗 

分 类 号：R734.2[医药卫生—肿瘤]