胃粘膜腺腔内脱落细胞及其粘液物质的病理研究  

Pathological Study of Exfoliated Cell and Mucous Substance of Glandular Cavity in Gastric Mucosa

作　　者：王仰坤[1] 王恩升 钟汉馨 王云玲 董荣春[1] 

机构地区：[1]第二军医大学病理学教研室

出　　处：《河南肿瘤学杂志》1996年第1期4-6,共3页Henan Journal of Oncology

摘　　要：对５６例胃粘膜腺体扩张和管状腺癌的腺腔内脱落细胞及粘液物质进行了研究。脱落细胞接形态特征分为增生上皮型、异型上皮型、核固缩型、核凋谢型和微核型五种。单纯性腺体扩张的腺腔内可见中性粘液、增生上皮型脱落细胞，而异型上皮型、核固缩型和微核型细胞偶见；异型性腺体扩张的腺腔内出现了硫酸粘液和唾液酸粘液，内有多量异型上皮型、核固缩型、核凋谢型和微核型脱落细胞，同胃管状腺癌基本一致。提示观察胃腺腔内脱落细胞的分型和粘液物质的变化有助于判定腺体扩张的病变性质和发展趋势。This study has assessed the exfoliated cells and mucous substance of glandular cavity in the gastric mucosa biopsied from 56 cases. The exfoliated cells were divided, according to morphological specialities, into five types, such as epithelial hyperplasic type,epithelial dysplasic type,pyknosis type,apoptosis type and microunclei type. In the glandular cavity of simple glandular expansion were seen neutral mucus and exfoliated cells of epithelial hyperplasic type and no or little cells of epithelial dysplasic type,pyknosis type and apoptosis type. In the glandular cavity of expansion was found sulfomucin or sialo-mucin substance,within which,a great number of the exfoliated cells of epithelial dysplasia type,pyknosis type,apoptosis type and micronuclei type existed. The dysplastic expansion and tubular adenocarcinoma were similar. The authors consider that the changes of the five types of exfoliated cells and mucous substances in the gastric glandular cavity can be of help in establishing a nature of pathological changes and developing tendence.

关 键 词：胃粘膜 腺体扩张 脱落细胞 粘液物质 鉴别诊断 

分 类 号：R735.2[医药卫生—肿瘤]