Synthesis of Novel C_(2)-Symmetrical Bidentate Phosphoramidite Ligands for Rh-catalyzed Asymmetric Hydrogenation of β-(Acylamino)acrylates  

作　　者：Qing Heng ZHNG Xiang Ping HU Xin Miao LIANG Zhuo ZHENG 

机构地区：[1]Dalian Institute of Chemical Physics,Chinese Academy of Sciences,Dalian 116023 [2]Graduate School of Chinese Academy of Sciences,Beijing 100039

出　　处：《Chinese Chemical Letters》2006年第6期711-713,共3页中国化学快报（英文版）

基　　金：The authors would like to thank the National Natural Science Foundation of China （No. 20472083） for financial support of this work.

摘　　要：Two new C2-symmetrical bidentate phosphoramidite ligands were synthesized and employed in the Rh-catalyzed asymmetric hydrogenation of β-（acylamino）acrylates, up to 89% ee with full conversions was obtained.Two new C2-symmetrical bidentate phosphoramidite ligands were synthesized and employed in the Rh-catalyzed asymmetric hydrogenation of β-（acylamino）acrylates, up to 89% ee with full conversions was obtained.

关 键 词：β-Aminoacid PHOSPHORAMIDITE 1 2-diphenylethylenediamine Rh-catalyzed asymmetric hydrogenation β-（acylamino）acrylates. 

分 类 号：O623.7[理学—有机化学]