PHOSPHORAMIDITE

作品数:11被引量:4H指数:2
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相关领域:理学生物学更多>>
相关期刊:《Wuhan University Journal of Natural Sciences》《Chinese Journal of Chemistry》《Precision Chemistry》《Tsinghua Science and Technology》更多>>
相关基金:国家自然科学基金中国科学院“百人计划”国家重点基础研究发展计划国家杰出青年科学基金更多>>
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Synthesis of RNA-Amphiphiles via Atom Transfer Radical Polymerization in the Organic Phase
《Precision Chemistry》2023年第5期326-331,共6页Jaepil Jeong Grzegorz Szczepaniak Subha R.Das Krzysztof Matyjaszewski 
NSF DMR 2202747 and DTRA grant HDTRA1-20-1-0014.G.S.gratefully acknowledges the Polish National Agency for Academic Exchange(BPN/PPO/2022/1/00027)for financial support。
The combination of hydrophobic polymers with nucleic acids is a fascinating way to engineer the self-assembly behavior of nucleic acids into diverse nanostructures such as micelles,vesicles,nanosheets,and worms.Here w...
关键词:ATRP RNA RNA-amphiphiles nucleic acid block copolymer RNA−polymer conjugate TBDMS SBiB PHOSPHORAMIDITE solid-phase RNA synthesis 
Platinum-Catalyzed Allylic C-H Alkylation with Malononitriles被引量:2
《CCS Chemistry》2022年第4期1366-1375,共10页Lian-Feng Fan Pei-Pei Xie Pu-Sheng Wang Xin Hong Liu-Zhu Gong 
The financial support from the National Nature Science Foundation of China(NSFC)(nos.21831007 and 21672197 for L.-Z.G.and nos.21702182 and 21873081 for X.H.);the Chinese Academy of Sciences(grant no.XDB20020000);Youth Innovation Promotion Association CAS,Fundamental Research Funds for the Central Universities(no.2020XZZX002-02 for X.H.);the State Key Laboratory of Clean Energy Utilization(no.ZJUCEU2020007 for X.H.)is gratefully acknowledged.
The direct functionalization of allylic C-H bonds is distinguished by enabling rapid assembly of structural complexity from simple molecules.Although Pd-catalyzed allylic C-H functionalization has been extensively stu...
关键词:platinum catalysis PHOSPHORAMIDITE C-H activation allylic alkylation concerted proton and two-electron transfer 
Atroposelective sp3 C—H Coupling for Kinetic Resolution of Thioanilide Atropisomers被引量:2
《Chinese Journal of Chemistry》2021年第12期3269-3276,共8页Hua-Jie Jiang Rui-Long Geng Jia-Hui Wei Liu-Zhu Gong 
We are grateful for the financial support from NSFC(Grant No.21831007).
A highly efficient kinetic resolution of racemic thioanilide atropisomers via C(sp^(3))-H arylation has been achieved by a hybrid palladium catalyst bearing an anionic chiral Co^(Ⅲ)-complex and a phosphoramidite liga...
关键词:Kinetic resolution C—H activation ATROPISOMERISM Chiral Co^(Ⅲ)-complex PHOSPHORAMIDITE 
A highly efficient fluorescence-based switch-on detection method of 5-formyluracil in DNA
《Nano Research》2017年第7期2449-2458,共10页Chaoxing Liu Yuqi Chen Yafen Wang Fan Wu Xiong Zhang Wei Yang Jiaqi Wang Yi Chen Zhiyong He Guangrong Zou Shaoru Wang Xiang Zhou 
We thank the National Basic Research Program of China (Nos. 2012CB720600 and 2012CB720603), the National Natural Science Foundation of China (Nos. 21432008, 91413109, and 81373256).
The identification of hydroxylmethyl- and formylpyrimidines in genomic DNA was a landmark event in epigenetics. Numerous laboratories in related fields are investigating the biology of these and other nucleic acid mod...
关键词:5-Formyluracil FLUORESCENCE PHOSPHORAMIDITE EPIGENETICS 
A novel method for the synthesis of sulfur substituted-cyclopyrophosphate of cADPR analogs
《Chinese Chemical Letters》2014年第12期1583-1585,共3页Ren-Min Wu Na Qi Yu-Wen Jia Zhu Guan Liang-Ren Zhang Li-He Zhang Zhen-Jun Yang 
scientific research funding from the National Natural Science Foundation of China(Nos.21332010,21172010, 21002004)
A facile and efficient protocol for the synthesis of sulfur substituted-cyclopyrophosphate of cIDPRE(P_S^1-cIDPRE) was developed.The key step was the cyclization process which was completed by the sulfur substituted...
关键词:cADPR cIDPRE Phosphoramidite strategy Cyclopyrophosphate 
Enantioselective Rh-Catalyzed Hydrogenation of N-Acyl Dehydroamino Esters and Enamides with Monodentate Phosphoramidite Ligands
《Wuhan University Journal of Natural Sciences》2009年第4期369-372,共4页LI Xinsheng,DING Qianchang,LI Liangchao, XU Dongcheng College of Chemistry and Life Sciences,Zhejiang Normal University,Jinhua 321004,Zhejiang,China 
Supported by the National Natural Science Foundation of China (20572101)
Chiral monodentate phosphoramidite ligands were conveniently prepared from 1,1'-bi-2-naphthol (BINOL) and (S)-pyrrolidine in good yields, which were effective chiral ligands in the enantioselective rhodium-cataly...
关键词:PHOSPHORAMIDITE chirality HYDROGENATION dehy- droamino ester ENAMIDE 
Synthesis of Novel C_(2)-Symmetrical Bidentate Phosphoramidite Ligands for Rh-catalyzed Asymmetric Hydrogenation of β-(Acylamino)acrylates
《Chinese Chemical Letters》2006年第6期711-713,共3页Qing Heng ZHNG Xiang Ping HU Xin Miao LIANG Zhuo ZHENG 
The authors would like to thank the National Natural Science Foundation of China (No. 20472083) for financial support of this work.
Two new C2-symmetrical bidentate phosphoramidite ligands were synthesized and employed in the Rh-catalyzed asymmetric hydrogenation of β-(acylamino)acrylates, up to 89% ee with full conversions was obtained.
关键词:β-Aminoacid PHOSPHORAMIDITE 1 2-diphenylethylenediamine Rh-catalyzed asymmetric hydrogenation β-(acylamino)acrylates. 
Synthesis of O -Phosphorylated Oligopeptides Using Phosphoramidite
《Tsinghua Science and Technology》2000年第2期163-166,共4页李艳梅 赵玉芬 
the National Natural Science Foundationof China! ( No.2 980 2 0 0 6) ;Chao Guangbiao High-Tech Fund!( No.97JC0 5 9
Reversible protein phosphorylation is of great importance in the regulation of many cellular processes. Structurally well defined compounds are needed for the study of the roles of the phospho proteins in biologica...
关键词:phosphorylated oligopeptide PHOSPHORAMIDITE OXIDATION SYNTHESIS 
A Facile Route for the Synthesis of Di-tert-butyl-N,N-dipropyl phosphoramidite
《厦门大学学报(自然科学版)》1999年第S1期204-204,共1页
关键词:A Facile Route for the Synthesis of Di-tert-butyl-N N-dipropyl phosphoramidite 
^(11)B and ~7Li NMR Investigations of the Oxysulfide Glasses in Li_2S-B_2O_3 (-LiBr) Systems
《Chinese Chemical Letters》1998年第12期0-0,0-0,共4页Hat Chun GAO Chan Gmin SUN and Yan HUO(Institute of Salt Lakes, Chinese Academy of Sciences, Xining 810008)Zi Rong LI (Institute of Physics, Chinese Academy of Sciences, Beijing 100080) 
Phosphopeptides were synthesized with bis-alkyloxy-N,N-dialkylphosphorfollowed by oxidation. Many hydroxyl groups in oligopeptides can be O-phosphorylated in onestep.
关键词:PHOSPHOPEPTIDE PHOSPHORAMIDITE 
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