老年人认知功能减退知情者问卷检测老年人认知功能损害  

Application of informant questionnaire on cognitive decline in the elderly in the screening of cognitive impairment in the elderly

作　　者：王姮[1] 张新卿[2] 汤哲[3] 周景升[2] 孙厚亮[2] 

机构地区：[1]空军总医院神经内科 [2]首都医科大学宣武医院神经内科,北京市100053 [3]流行病学研究中心与社会医学部

出　　处：《中华老年医学杂志》2006年第5期386-388,共3页Chinese Journal of Geriatrics

摘　　要：目的评价老年人认知功能减退知情者问卷在中国老年人群中应用的信效度,以及在认知功能损害筛查中的有效性。方法认知功能损害患者93例,应用简短版本的老年人认知功能减退知情者问卷(IQCODE)对其知情者进行问卷调查。对128名60岁以上来自于社区的健康老年人的知情者进行调查,作问卷的信效度检验。结果 IQCODE 内部一致性系数达0.83。重测信度Pearson 相关系数为0.86。与简短精神状态量表(MMSE)、日常生活活动能力量表(ADL)的效度系数分别为-0.78和0.71。IQCODE 得分在轻度认知障碍和轻、中、重度痴呆患者中分别为(3.5±0.4)分和、(4.2±0.4)分、(4.7±0.2)分和(4.9±0.2)分,差异有统计学意义,但在阿尔茨海默病(AD)和血管性痴呆(VaD)等不同痴呆病因组间差异无统计学意义。结论 IQCODE 信效度良好。得分与病情严重程度密切相关,此问卷能将痴呆和轻度认知功能损害患者与健康人群很好地区分开来,可用于认知功能损害的检测。但对 AD、VaD 等痴呆类型的鉴别作用有限。Objective To evaluate the reliability and validity of informant questionnaire on cognitive decline in the elderly（IQCODE） in Chinese elderly patients and to estimate the efficacy of IQCODE in the screening of patients with cognitive impairment. Methods Ninety three patients with cognitive impairment and 128 community-dwelling healthy elderly over 60 years old were assessed. Informants were interviewed with the short version of the IQCODE. Results The internal consistency coefficient of IQCODE was 0.83. The correlation coefficient of test-retest reliability was 0.86. The validity coefficient of IQCODE with mini-mental state examination and activities of daily living were -0. 78 and 0. 71 respectively. The scores of IQCODE of the patients varied with the degree of cognitive deficits, and the differences had statistical significance. But there was no significant difference among different types of senile dementia. The scores of IQCODE of the patients with cognitive impairment were closely correlated with the degree of cognitive deficits. Conclusions IQCODE is a reliable and effective measurement for the patients with cognitive impairment. It could discriminate the cognitive impairment patients from the normal cognitive ones, and is practical in screening. But it can not distinguish different kinds of dementia.

关 键 词：认知障碍 痴呆 问卷调查 老年人 

分 类 号：R749.1[医药卫生—神经病学与精神病学]