丝裂霉素C对高度近视患者LASEK术后Haze形成的影响  

Effects of mitomycin-C on Haze formation after LASEK on patients with high myopia

作　　者：邓德向[1] 袁小江[1] 王凤娥[1] 

机构地区：[1]湖南省怀化市第一人民医院眼科,418000

出　　处：《眼科新进展》2006年第6期454-455,共2页Recent Advances in Ophthalmology

摘　　要：目的观察丝裂霉素C对高度近视患者准分子激光上皮下角膜磨镶术(LASEK)术后角膜上皮下混浊(Haze)发生程度的影响,从而寻找更好的能防止Haze发生的方法。方法将术中应用丝裂霉素C的48例90眼高度近视患者列为丝裂霉素组,随机抽取术中未应用丝裂霉素C的54例90眼高度近视患者为常规治疗组,分别于术后1月、3月、6月将患者角膜Haze发生、发展情况进行比较。结果丝裂霉素组的高度近视患者术后不同时期Haze发生程度较常规治疗组的高度近视患者低,2者具有显著性差异(P<0·01)。结论丝裂霉素C对高度近视患者LASEK术后Haze的形成具有明显的抑制作用。Objective To observe the effect of mitomycin-C on degree of Haze under corneal epithelium after laser subepithelial keratomileusis （LASEK） in patients with high myopia, to find out better methods to prevent Haze from coming into being. Methods Forty-eight cases （90 eyes） patients with high myopia were used mitomycin-C as mitomycin group, 54 cases （90 eyes ）patients with high myopia weren＇t used mitomycin-C as routine group. The occurence and development of Haze were compared between two groups at 1 month, 3 months, 6 months separately postoperative. Results The degree of Haze occurred in mitomycin-C group was obviously lower（P〈0.01 ） than the routine group at different times. Conclusion Mitomycin-C was obviously effective to prevent Haze from coming into being.

关 键 词：丝裂霉素C 准分子激光 上皮瓣下磨镶术 

分 类 号：R778.1[医药卫生—眼科] R779.6[医药卫生—临床医学]