复方当归注射液的质量控制方法研究  

Quality Control of Compound Angelica Injection

作　　者：唐海英[1] 马传新[1] 

机构地区：[1]解放军第89医院,潍坊市261021

出　　处：《中国药房》2006年第11期854-856,共3页China Pharmacy

摘　　要：目的：建立复方当归注射液的质量控制方法.方法：采用薄层色谱法对复方当归注射液中当归、川芎、红花、丹参、葛根5种主要药材进行定性鉴别;采用高效液相色谱法测定当归、川芎中阿魏酸的含量.结果：在薄层色谱中能检测出上述5种主要药材;阿魏酸检测浓度在2.829～15.990mg/L范围内线性关系良好（r=0.9 996）,平均加样回收率为99.34%（RSD=0.94%）.结论：本方法重现性好,可用于复方当归注射液的质量控制.OBJECTIVE： To establish a method for the quality control of compound angelica injection.METHOD： 5 main Chinese crude drugs, i.e.angelica, chuanxiong, flos carthami, salvia miltiorrhiz and pueraria in compound angelica injection were identified qualitatively by TLC;The contents of ferulic acid in angelica and chuanxiong were determined by HPLC .RESULTS：The above mentioned 5 main Chinese crude drugs were detected by TCL.Ferulic acid showed a good linearity in a range of 2.829--15.990mg/ L（ r = 0.9 996）, the average recovery rate was 99.34% （RSD = 0.94% ） .CONCLUSION： This method has a good reproducibility and suitable for the quality control of compound angelica injection.

关 键 词：复方当归注射液 阿魏酸 薄层色谱法 高效液相色谱法 

分 类 号：R927.11[医药卫生—药学]